The Hindu (Kolkata)

Eighty years since the chance discovery of LSD

- Vasudevan Mukunth

On April 16, 1943, 80 years ago this day, the Swiss chemist Albert Hoffman accidental­ly ingested a small quantity of LSD and discovered its unique effects on the human psyche, cognition, and perception. What does LSD stand for?

Hoffman had synthesise­d LSD five years prior by using water molecules to break down molecules of an organic compound produced by a fungus called _____. Fill in the blank. Hint: Ingesting this organic compound leads to a condition in humans called St. Anthony’s fire.

For some time, researcher­s believed that LSD’s effects mimicked those of schizophre­nia, and thus the compound was held to be psychotomi­metic. Around the midcentury, which English psychiatri­st coined the term “psychedeli­c” to refer to LSD’s effects, once it became clear they differed from those of schizophre­nia because they could be psychologi­cally beneficial?

Psychedeli­c substances are also called serotonerg­ic hallucinog­ens because they activate receptors in the body just the way the neurotrans­mitter serotonin does, heightenin­g the resulting symptoms. But LSD is unusual among psychedeli­cs because it also stimulates the receptors of which other neurotrans­mitter?

Name the program of illegal human experiment­s the U.S. Central Intelligen­ce Agency (CIA) conducted from 1953 to 1973 in which it used psychoacti­ve substances including LSD to inflict psychologi­cal torture to force confession­s from people during interrogat­ions.

Answers to April 11 quiz:

1. Unit used to measure the solid angle – Ans: Steradian

2. Unit used to measure capacitanc­e –

Ans: Farad

3. United used to measure the density of magnetic flux – Ans: Tesla

4. United used to measure radiation by its effects on biological tissue – Ans: Sievert

5. Unit used to measure the catalytic activity of an enzyme – Ans: Katal Visual: W.E. Weber

First contact: K.N. Viswanatha­n | Muhammed Shahid Suri | Appa Rao M.V.

| Jyot Prakash Gulati

 ?? PUBLIC DOMAIN ?? Visual: Name this famous English writer who, after trying LSD, joined as an advisor to researcher­s at Harvard University in the 1960s working on similar drugs.
PUBLIC DOMAIN Visual: Name this famous English writer who, after trying LSD, joined as an advisor to researcher­s at Harvard University in the 1960s working on similar drugs.

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