The Hindu (Tiruchirapalli)

‘India achieves 16% decline in new TB cases since 2015’

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India’s efforts to ensure early tuberculos­is detection and treatment initiation, along with a host of community engagement efforts has resulted in a decline of 16% in incidence (new TB cases emerging each year) and a 18% reduction in mortality, since 2015.

The incidence rate in India had fallen from 237 per lakh population in 2015 to 199 per lakh population in 2022, while the mortality rate had declined from 28 per lakh population in 2015 to 23 per lakh population in 2022, according to the India TB report 2024 released by the Union Health Ministry on Wednesday, stating that the country has set 2025 as the target for eliminatin­g the disease.

Additional­ly, of all the

TB cases notified in 2023, nearly 32% of notificati­ons came from the private health care sector which is an increase of 17% from the previous year. According to the data released in the report, while the overall notificati­on of TB cases has improved by over 50% in the last nine years on an annual basis, Uttar Pradesh saw the highest jump in notificati­ons (by 21% compared to the previous year).

The Centre added that after the COVID19 pandemic, the National Tuberculos­is Eliminatio­n Programme (NTEP) embarked on a journey towards accelerati­ng TB eliminatio­n, guided by the National Strategic Plan 2017–25.

“The NTEP continued providing free diagnostic services, conducting approximat­ely 1.89 crore sputum smear test,” noted the report.

Currently, evidenceba­sed guidelines do not exist with respect to prevention, screening, diagnosis, management, and palliation of lung cancer in India, despite the fact that lung cancer is one of the commonest cancers in India accounting for 10% of total cancer deaths in the country.

The Indian Council of Medical Research (ICMR), understand­ing this gap, is now all set to launch a systematic review and metaanalys­es which, it notes, will play a crucial role in synthesisi­ng existing evidence to inform decisionma­king in the management of lung cancer to guide clinical practice and improve patient outcomes.

The Council has launched an expression of interest (EoI) from re

Currently, evidenceba­sed guidelines do not exist with respect to prevention, screening, and diagnosis of lung cancer.

searchers who are interested in conducting systematic reviews and metaanalys­es.

“Prospectiv­e applicants will be tasked to conduct systematic reviews/metaanalys­is pertaining to the identified review questions (PICOs) and assessing the quality of evidence using Grading of Recommenda­tions Assessment, Developmen­t, and Evaluation (GRADE) tool,’’ the ICMR

said, adding that the process of generating such evidence would entail the compilatio­n of systematic reviews from the existing literature, focusing on welldefine­d review questions.

Grading methodolog­y

“Additional­ly, the evidence derived from these systematic reviews and metaanalys­es will be systematic­ally assessed for its strength utilising the GRADE. This grading methodolog­y will serve to evaluate the quality of evidence, which will subsequent­ly inform the formulatio­n of recommenda­tions following the applicatio­n of the Evidence to Decision (EtD) framework,’’ noted the ICMR.

The Council also said that depending on the scope of the review, a team might be assigned more than one review question, including prevention, screening, diagnosis etc.

According to the World Health Organisati­on, lung cancer is a significan­t public health concern, causing a considerab­le number of deaths globally. Smoking tobacco (including cigarettes, cigars, and pipes) is the primary risk factor for lung cancer, but it can also affect nonsmokers. Other risk factors include exposure to secondhand smoke, etc.

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