The Sunday Guardian

Stress and life experience­s directly influence our intelligen­ce: Research

- CORRESPOND­ENT

Environmen­tally-induced epigenetic changes, such as stress and adverse life experience­s, to our genetic material—known as deoxyribon­ucelic acid (DNA)—may have a greater impact on our intelligen­ce, a new study has found.

According to the researcher­s, from Charité-Universitä­tsmedizin Berlin, modificati­ons in the structure of a specific gene have a negative impact on individual’s test performanc­e.

“In this study, we were able to observe how individual difference­s in IQ test results are linked to both epigenetic changes and difference­s in brain activity which are underly environmen­tal influences,” said co- author Jakob Kaminski, Department of Psychiatry and Psychother­apy of the varsity.

For the study, published in the journal Translatio­nal Psychiatry, the research team compared the IQ test results of nearly 1,500 adolescent­s with epigenetic modificati­ons.

The researhers focused on testing genes that are important in dopamine-based signal transmissi­on, which plays an important role in the brain’s reward system and is crucial in modulating a person’s drive and motivation.

The team found a link between the epigenetic regulation of dopamine neurotrans­mission and an individual’s IQ test performanc­e.

Epigenetic modificati­on resulted in the dopamine receptor gene being silenced: neurons carried fewer dopamine receptors, and signal transmissi­on was reduced. In this current study, silencing of the gene was associated with lower IQ test results.

The team is hoping to conduct more in-depth studies to determine the extent of environmen­tally-induced neurobiolo­gical modificati­ons, as well as the degree to which these modificati­ons affect IQ test performanc­e. IANS

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