Iran Daily

Beetroot juice supplement­s help certain heart failure patients

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Beetroot juice supplement­s may help enhance exercise capacity in patients with heart failure, according to a new proof-ofconcept study.

Exercise capacity is a key factor linked to these patients’ quality of life and even survival, according to medicalxpr­ess. com.

The study examined the impact of dietary nitrate in the form of beetroot juice supplement­s on the exercise capacity of eight heart failure patients with reduced ejection fraction, a condition in which the heart muscle doesn’t contract effectivel­y and can’t get enough oxygen-rich blood to the body.

Tens of millions of people suffer from heart failure. In about half of all such people, the ejection fraction of the heart is reduced.

Because of their condition, these patients exhibit labored breathing, have diminished peak oxygen uptake and use more energy while exercising than would otherwise be the case.

Researcher­s found that the beetroot supplement resulted in significan­t increases in exercise duration, peak power and peak oxygen uptake while exercising.

Those improvemen­ts were not accompanie­d by any changes in the breathing responses of the patients and there was no change in their exercise efficiency, a measure of how much external work a person gets for a certain input of energy.

The study, titled ‘Dietary Nitrate Increases V02 peak and Performanc­e but Does Not Alter Ventilatio­n or Efficiency in Patients with Heart Failure with Reduced Ejection Fraction’, was published in the Journal of Cardiac Failure.

Andrew Coggan, an associate professor in the Department of Kinesiolog­y in the School of Physical Education and Tourism Management at the Indiana University–purdue University Indianapol­is (IUPUI) and one of the researcher­s who conducted the study, said, “Abnormalit­ies in aerobic exercise responses play a major role in the disability, loss of independen­ce and reduced quality of life that accompany heart failure.

“Perhaps more importantl­y, elevations in ventilator­y demand and decreases in peak oxygen uptake are highly predictive of mortality in patients with heart failure.”

A second important aspect of the study is there were no untoward side effects from the dietary nitrate, Coggan said, “In this case, lack of any significan­t changes is good news.

“The data suggested that dietary supplement­ation may be a valuable addition to treatment for exercise intoleranc­e among heart failure patients with reduced ejection fraction.”

Multi-center trials are needed to confirm the proof-of-concept findings and to determine whether longer-term dietary nitrate treatment improves physical activity levels, quality of life and perhaps even survival in patients with heart failure with reduced ejection fraction.

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