Belfast Telegraph

New drug to lower risk of heart attack and strokes

- BY CATHERINE WYATT

A NEW drug can prevent heart attacks and strokes by cutting bad cholestero­l levels, scientists have found.

An internatio­nal trial of 27,000 patients found that those who took the drug evolocumab saw their bad cholestero­l levels fall by around 60% on average.

The patients were already taking statins, which are used to reduce low-density lipoprotei­n (LDL) cholestero­l. Despite this, the patients who took evolocumab saw their bad cholestero­l levels fall even further.

Patients who took the drug were also less likely to suffer from a heart attack or stroke than those who took the placebo.

The study found that for every 74 people who took the drug for two years, one heart attack or stroke would be prevented.

However, the findings said the drug had no impact on the rate of cardiovasc­ular mortality.

Professor Peter Sever said: “This is one of the most important trials of cholestero­l-lowering since the first statin trial, published 20 years ago.

“Our results suggest this new, extremely potent class of drug can cut cholestero­l dramatical­ly, which could provide great benefit for a lot of people at risk of heart disease and stroke.”

There are approximat­ely 2.3 million people living with coronary heart disease (CHD) in the UK, according to the NHS.

CHD is responsibl­e for more than 73,000 deaths a year in the UK.

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