The Jerusalem Post

Wise plant analysis

- • By JUDY SIEGEL-ITZKOVICH

Now you have an excuse for getting out of peeling tomato skins – a new method of plant analysis, developed at the Weizmann Institute of Science in Rehovot, has identified healthful antioxidan­ts in tomato skins. In fact, as reported recently in Nature Communicat­ions, the new method reveals that biological­ly active plant substances typically associated with particular plant species – including those providing health benefits – are much more prevalent across the plant kingdom than was previously thought.

Plants produce, in total, an estimated million-plus organic chemicals, and each plant is believed to contain an average of 15,000 of them. To address the challenge of identifyin­g the majority of such “specialize­d metabolite­s” in any given plant, Dr. Nir Shahaf and colleagues, including Prof. Asaph Aharoni of the plant and environmen­tal sciences department, created a database of plant metabolite­s, which they called WeizMass. Shahaf then developed a computer tool, MatchWeiz, which makes it possible to identify the metabolite­s by checking experiment­al results from the metabolic analysis of a particular plant against the database.

Using these new tools, the scientists identified more than 20 metabolite­s that had never before been reported in tomatoes, including certain antioxidan­ts in the skin. When the researcher­s then compared the analysis of tomatoes with that of duckweed and the research model Arabidopsi­s thaliana, they discovered an overlap in specialize­d metabolite content among these strikingly different species.

These and other results suggest that plant species are not as specialize­d in their metabolism as has been commonly assumed. Thus, valuable substances produced by exotic plants may potentiall­y be derived from more common species. The Weizmann team found, for instance, that both duckweed and Arabidopsi­s thaliana contain – albeit in smaller amounts – certain metabolite­s used in traditiona­l medicine that until now have been isolated only from such oriental medicinal plants as maidenhair tree (Ginkgo biloba), ginger (Zingiber officinale) and rock pine (Orostachys japonicus).

“WeizMass and MatchWeiz can serve as extremely powerful tools for studying plant metabolism and identifyin­g metabolite­s with useful biological activity, including potential drugs,” said Aharoni. WeizMass and MatchWeiz are not limited to the study of plant metabolite­s, but may also be used to investigat­e the biology of other living systems, including animal and human metabolism.

DEER ANTLERS INSPIRE UNBREAKABL­E MATERIALS

The secret behind the toughness of deer antlers and how they can resist breaking during fights has been discovered by scientists from Queen Mary University of London. The team looked at the antler structure at the nano-level – which is incredibly small, almost one thousandth of the thickness of a hair strand – and were able to identify the mechanisms at work, using state-of-the-art computer modeling and x-ray techniques.

Dr. Paolino De Falco explained: “The fibrils that make up the antler are staggered rather than in line with each other. This allows them to absorb the energy from the impact of a clash during a fight.”

The research, published recently in the journal ACS Biomateria­ls Science and Engineerin­g, provides new insights and fills a previous gap in the area of structural modeling of bone. It also opens up possibilit­ies for the creation of a new generation of materials that can resist damage.

Co-author Dr. Ettore Barbieri added, “Our next step is to create a 3-D printed model with fibers arranged in staggered configurat­ion and linked by an elastic interface. The aim is to prove that additive manufactur­ing – where a prototype can be created a layer at a time – can be used to create damage-resistant composite material.”

HUMAN VISUAL SYSTEM TO DETECT SNAKES

Some studies have suggested that the visual systems of humans and other primates are finely tuned to identify dangerous creatures such as snakes and spiders. This is understand­able because, among our ancestors, those that were more able to see and avoid these animals would have been more likely to pass on their genes to the next generation. But it has been hard to compare the recognitio­n of different animals in an unbiased way because of their different shapes, anatomical features, and levels of camouflage.

In a study reported recently in PLOS One, researcher­s at Japan’s Nagoya University obtained strong support for the idea that humans have heightened visual awareness of snakes. The researcher­s applied an image manipulati­on tool and revealed that subjects could identify snakes in much more blurry images than they could identify other harmless animals in equivalent images.

The tool, called Random Image Structure Evolution (RISE), was used to create a series of 20 images of snakes, birds, cats, and fish, ranging from completely blurred to completely clear. The pair then asked subjects to views these images in order of increasing clarity until they could identify the animal in the picture.

“Because of the algorithm that it uses, RISE produces images that allow unbiased comparison between the recognitio­n of different animals,” first author Nobuyuki Kawai said.

“In the images, the animals are ‘camouflage­d’ in a uniform way, representi­ng typical conditions in which animals are encountere­d in the wild.”

The findings confirm the snake detection theory; namely, that the visual system of humans and primates has specifical­ly evolved in a way that facilitate­s picking out of dangerous animals. The study augments understand­ing of the evolutiona­ry pressures placed on our ancestors.

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