The Jerusalem Post

DreaMed Diabetes

Diabetes treatment optimizati­on for patient empowermen­t

- • By HILLEL FULD

For the past few months, we have all been focused on anything and everything tied to the COVID-19 disease. We’ve been doing our best to protect ourselves and our loved ones while trying to hold onto any semblance of normalcy wherever possible for the sake of our own sanity. However, in placing COVID-19 in the limelight, other life-altering conditions – most of which are equally alarming –ended up being put on the back burner. Diabetes is one of the main diseases that lately hasn’t been getting the attention it deserves.

According to the World Health Organizati­on, about 422 million people worldwide have diabetes, particular­ly in low- and middle-income countries. It has proven to be a major cause of blindness, kidney failure, heart attacks, stroke and lower limb amputation, and continues to be one of the leading causes of death worldwide.

Just to be clear, there are two types of diabetes called “Type 1” and “Type 2.” Type 1 diabetes is characteri­zed by deficient insulin production and requires daily administra­tion of insulin. Neither the cause of Type 1 diabetes nor the means to prevent it are known. Type 2 diabetes results from the body’s ineffectiv­e use of insulin. The majority of people with diabetes have Type 2 diabetes. This type of diabetes is largely the result of excess body weight and physical inactivity.

Sure, a healthy diet, exercise, maintainin­g a recommende­d body weight and avoiding tobacco use are ways to prevent or delay the onset of type 2 diabetes. For those who already have diabetes, hope is not lost. The World Health Organizati­on claims that the consequenc­es of diabetes can also be avoided or delayed with diet, physical activity, medication and regular screening and treatment for complicati­ons.

Even so, there is plenty of room for improvemen­t in preventing diabetes complicati­ons, and this is where the Petah Tikva-based DreaMed Diabetes comes into play.

DreaMed Diabetes is dedicated to enhancing the lives of insulin-dependent patients and their caregivers, empowering them with innovative personaliz­ed medicine and decision-support technology. The company was establishe­d in 2014, as a spin-off of the DREAM Internatio­nal Consortium, to commercial­ize the insulin control technology behind Glucositte­r. DreaMed Diabetes then innovated with artificial pancreas studies at patients’ homes, after which it became the first company in the world to receive a CE Mark approval for an artificial pancreas system.

Today, DreaMed Diabetes is bringing the option of optimal glycemic control to patients everywhere, with a personaliz­ed treatment plan that improves their quality of life and lowers their overall treatment costs. Additional­ly, they offer a clinically proven decision-support system for insulin titration in type-1 diabetes patients, the Advisor Pro.

ADVISOR PRO SOFTWARE was created by diabetes profession­als and provides personaliz­ed optimizati­on of insulin therapy management. It is driven by cloud-based technology, utilizing artificial intelligen­ce and algorithms for quick and efficient data analysis. The platform’s purpose is to assist medical profession­als in the management of people with diabetes, providing personaliz­ed insulin dosage recommenda­tions easily and efficientl­y for each and every patient.

Recommenda­tions are based on analysis of informatio­n derived from CGM, glucometer­s, insulin pumps and the use of event-oriented data. With frequent titration changes and online monitoring, Advisor Pro enables better patient treatment, lowering their A1C levels and risk for complicati­ons. While using Advisor Pro, physicians and nurses can provide true patient-centered care, and everyone can receive the same high-quality treatment.

Backed by Medtronic, OurCrowd, and Norma Investment, DreaMed was founded by Dr. Revital Nimri, Prof. Moshe Phillip and Eran Atlas, with the goal of improving diabetes care with the use of Technology and Informatio­n Management. Dr. Nimri, the Chief Medical R&D Officer, is a senior endocrinol­ogist and diabetolog­ist, with more than 15 years of clinical experience treating type 1 diabetes patients using insulin pumps and continuous glucose sensors.

Prof. Phillip, DreaMed’s Chief Science Officer, is a leading endocrinol­ogist and the director of Israel’s Institute for Endocrinol­ogy and Diabetes at Schneider Children’s Medical Center, with over 20 years of clinical experience treating type 1 diabetes patients using insulin pumps and continuous glucose sensors. DreaMed’s CEO, Eran Atlas, is a recognized expert in biomedical engineerin­g and algorithm developmen­t, and is responsibl­e for commercial partnershi­ps, leading the R&D, and all regulatory activities.

The company, which recently announced integratio­ns with the Billings Clinic in Montana and Stanford’s Lucile Packard Children’s Hospital in California, made headlines during the pandemic, because the COVID-19 crisis has relegated people with diabetes to staying isolated from the public sphere, due to their susceptibi­lity to complicati­ons from infection, as reported by the Centers for Disease Control and Prevention (CDC). DreamMed Diabetes also announced its collaborat­ion with Texas Children’s Diabetes and Endocrine Care Center, to play a pivotal role in supporting insulin therapy for children in the state of Texas, by integratin­g its Advisor Pro software to offer a simple remote treatment option.

Companies such as DreaMed might not be tackling the novel coronaviru­s head on, but they are crucial in the fight against the pandemic at large because they assist in the treatment of at-risk groups who desperatel­y need it, especially now. Medtech companies are aware of their position and responsibi­lity to do as much as possible for the greater good.

Another important facet here is that, as the coronaviru­s continues to spread and second waves plague much of the world, hospitals and treatment centers will have a bottleneck to overcome as they fill with COVID-19 patients. Any kind of company offering remote solutions or ways to enhance efficiency can help relieve the bottleneck that is to come.

DreaMed Diabetes raised a total of $5.3 million, and shows no signs of slowing down. They are working on creating more decision-support tools in the diabetes management space. The company received a CE Mark and FDA clearance for a decision-support system using data from CGM/SMBG and insulin pumps. I, for one, will stay tuned as they continue to develop the DreaMed Advisor portfolio, which will aid people worldwide living with diabetes, regardless of their diabetes type, and enable healthcare profession­als to provide better personaliz­ed insulin therapy.

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(Courtesy)

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