The Jerusalem Post

Shaare Zedek continues to break through healthcare barriers

- • By HILLEL FULD

Over the past year and a half, I’ve written countless columns about disruptive Israeli tech companies in the medical space. Israel has truly become a leader in using innovation to revolution­ize healthcare.

Companies like Zebra Medical, Healthy.io, MobileODT and so many others have developed proprietar­y technology that is saving lives every single day.

Any CEO of a healthcare tech company will tell you that the Holy Grail is data. Without data, no medical innovation­s would be possible. Of course, data are not only important in this specific field, and it’s been said that data are the new oil, but when it comes to healthcare, the importance of data is magnified tenfold.

So who has access to the data that facilitate all this innovation? Hospitals.

I’ve heard of several collaborat­ions between tech companies, venture capitalist­s, and hospitals, but when I heard about what Jerusalem’s Shaare Zedek Medical Center was doing, I had to learn more.

For the sake of transparen­cy, I have to say that I have personally had many positive experience­s with Shaare Zedek over the years, including my wife giving birth there, as well as family members being treated in the hospital. So when I heard that Shaare Zedek had begun embracing partnershi­ps for technology developmen­t, I was interested not only from a profession­al standpoint, but also from a personal one.

As a hospital that treats more than 800,000 cases per year, Shaare Zedek, which opened in 1902, has long-been known as an internatio­nally leading center of advanced patient care and medical research. Recognizin­g the growing interactio­n between medical providers and the tech sector, in 2018 the hospital made the decision to launch its own Innovation Center to harness the hospital’s experience and available data to help develop the next generation of medical innovation­s.

The Innovation Center, under the name Madait, or Shaare Zedek Scientific, has already establishe­d working relationsh­ips with many leading tech companies that recognize when it comes to product developmen­t, particular­ly in the medical sector, access to data is the critical tool for testing purposes. The company is a for-profit venture, but owned by the medical center where it is housed and operates, profits are directed to support the operating budget of the hospital. While most of the efforts of the company are focused on collaborat­ions with partners in the technology sector, they have also been involved with supporting research within the hospital to develop new pharmaceut­ical products that are already in widespread use around the world.

The main visionary who has overseen the developmen­t of the company and now serves as its chair is Prof. Dan Turner. A pediatric gastroente­rologist, Turner is a highly-accomplish­ed researcher who recognized that the hospital had enormous potential to act as a technology innovator.

“We understand that when it comes to forward developmen­t, data is everything. So we are able to not only provide massive troves of data but we also have the tools and human resources to make that data relevant for leading technology companies.”

The day to day implementa­tion of that vision is now in the hands of Dr. Renana Ofan, who serves as the company’s CEO. With a background in neuroscien­ce and biology, Dr. Ofan studied at the Hebrew University of Jerusalem before pursuing a PhD at New York University.

“Shaare Zedek is able to offer tech partners an incredibly valuable tool in that we are essentiall­y operating one of the world’s most valuable testing laboratori­es with the data made available from hundreds of thousands of cases per year, as well as our team of physicians and researcher­s,” explains Dr. Ofan. “Our role in the technology developmen­t process is to serve as an enabling partner whereby we provide access to patients and data that can be tested in a real clinical setting.”

WHILE MANY of the details of the partnershi­ps remain protected by confidenti­ality agreements as the research

collaborat­ions are ongoing, the company says that it has already worked with leading industry players like Google and Medtronic and each year adds dozens of new companies to its rosters of working partnershi­ps. According to the company, its portfolio of partners increased nearly four-fold in 2020 over 2019.

The onset of the coronaviru­s presented Shaare Zedek with a major challenge to respond to the pandemic, but the heads of Madait immediatel­y recognized the massive research potential that the hospital would be possessing. Over the course of the coming months, the hospital would become the most active corona hospital in Israel with more than 5,000 patients treated on an inpatient basis and thousands more treated and released without need for hospitaliz­ation. All the patient data was gathered into a central “biobank” representi­ng tens of thousands of data samples that have since been relied upon for dozens of studies by developers in Israel and other parts of the world.

Among the ongoing tech collaborat­ions has been with the Israeli-based Sight Diagnostic­s, which developed a tool called Sight OLO that combines artificial intelligen­ce, image-processing technologi­es and proven blood diagnostic tools to be able to perform a complete blood count (CBC) with just several drops of blood and the results returned within minutes. This technology has the potential to act as a revolution in diagnostic medicine by replacing timely and costly tests that

require far more substantia­l amounts of blood with this very simple and non-invasive approach.

Shaare Zedek Scientific has also partnered with the Japanese tech giant NEC in testing the developmen­t of a device that can monitor key vital signs for patients upon arrival in an emergency department without the need for any physical contact with the patient. The patient simply stands in front of the device, which is then able to monitor key signs like heart rate, breathing irregulari­ties and temperatur­e even before a nurse or doctor assesses the patient.

Dr. Todd Zalut, director of Shaare Zedek’s Department of Emergency Medicine, described the collaborat­ion as a game-changer, saying, “When this system is introduced into widespread use in urgent care facilities, it will save a great amount of time and free up staff members to focus on other areas of treatment. It will also allow us to more quickly direct patients to the specific treatment areas

and allow them to get the care they need that much more quickly.”

Elad Goz, head of the Innovation Center, says that Madait’s growth strategy is heavily focused on the area of digital health.

“Our experience since our launch has proven that the data that we have to offer companies can directly contribute to the developmen­t of new devices, methods of care and even new drugs. More than ever before, the technology sector knows that partnershi­ps with clinical entities like ours are a critical path to success so we welcome the opportunit­y for continued expansion and growth in ways that we know will benefit the advancemen­t of technology and the healthcare community at large.”

Given Shaare Zedek’s massive amounts of available data combined with its forward thinking technology-adopting mentality, the sky’s the limit to what Shaare Zedek Scientific can accomplish. I for one am excited to see what the team does next.

 ??  ?? JERUSALEM’S SHAARE ZEDEK Medical Center processes more than 800,000 patient visits per year. (Ezra Landau)
JERUSALEM’S SHAARE ZEDEK Medical Center processes more than 800,000 patient visits per year. (Ezra Landau)
 ??  ?? DR. RENANA OFAN
(Courtesy Shaare Zedek Medical Center, Jerusalem)
DR. RENANA OFAN (Courtesy Shaare Zedek Medical Center, Jerusalem)
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