The Jerusalem Post

Slaying the superbug

Leveraging antimicrob­ial textiles to fight antimicrob­ial-resistance

- • By LIAT GOLDHAMMER The writer is CTO of Sonovia.

Antimicrob­ial-resistance (AMR) is winning, reaching dangerous levels due to the overuse and misuse of antimicrob­ials. AMR-related healthcare-associated infections are leading to longer hospital stays, reduced quality of life and disability, higher death rates and higher economic costs. The World Health Organizati­on has proclaimed AMR to be one of the top 10 global public health threats facing humanity.

According to the CDC’s “2019 Antibiotic­s Resistance Threats in the US” report, there are more than 2.8 million yearly antibiotic-resistant infections and more than 35,000 deaths per year as a result in the United States alone. Treating infections caused by six common drug-resistant germs amounts to more than $4.6 billion in annual national costs.

Our ability to treat and cure once-simple diseases is becoming compromise­d unless we find new, effective ways to eradicate AMR pathogens. With the frequent mutation and adaptation of pathogens to medication, other means of fighting AMR must be incorporat­ed to reduce the levels of resistant microbes in the environmen­t. Common public areas such as public transporta­tion and public transporta­tion hubs, hotels, hospitals and healthcare facilities, restaurant­s, etc., contain hightouch textiles and fabrics that can quickly spread infection. Antimicrob­ial textiles provide another means to effectivel­y reduce pathogen levels in human surroundin­gs.

Antimicrob­ial fabrics are fabrics that have been treated to be functional­ly active in killing microorgan­isms or in inhibiting their growth. This can be achieved in a number of ways and methods of treatment, usually by impregnati­ng or coating textiles with antimicrob­ial compounds through leaching or non-leaching methods. The most common method of leaching antimicrob­ial compounds loses potency over time with each wash cycle, quickly reaching below-lethal levels and hence becoming ineffectiv­e.

Sonovia uses innovative patented ultrasonic cavitation technology to forcefully blast textiles with metallic oxide compounds. The sheer force of the cavitation process embeds the antimicrob­ial compounds within the textile’s structure, providing long-lasting performanc­e and potency. In fact, lab results show that Sonovia’s treated antimicrob­ial fabrics maintain their potency for over 55 washes. Sonovia’s technology is eco-friendly and requires no harmful chemical binders, conserving precious drinking water in its process compared with the prevalent antimicrob­ial finishing methods on the market. The innovative method can be applied to any type of textile material.

Sonovia was founded in 2013 following a successful four-year EU-funded research which included an indicative clinical trial in a European hospital to prove the efficacy of the technology in dramatical­ly reducing or eliminatin­g HAI levels. The clinical trial was declared a huge success, with healthcare-associated infections decreasing dramatical­ly through the use of the antimicrob­ial textiles and uniforms. Sonovia is currently partnering with leaders in the automotive industry to apply its antimicrob­ial fabrics to vehicle interior components. Sonovia’s masks with antimicrob­ial fabric have been proven to neutralize fungi, bacteria and viruses including SARS-CoV-2 and its variants including the UK variant and now dominant Delta variant with over 99% efficacy. Professor Amos Adler, Sonovia’s scientific adviser and director of the Clinical Microbiolo­gy Laboratory at the Tel Aviv Sourasky Medical Center (TASMC) said:

“COVID-19 variants might have different epidemiolo­gical or immunologi­cal properties that are the result of point mutations in critical areas of the receptor binding domain. Still, their overall structure and biophysica­l properties of the virus are almost identical. Hence, the antiviral effect exerted by the Sonovia-treated fabrics is expected to be present in all COVID-19 variants.”

Sonovia is working tirelessly to continue implementi­ng its vision of saving lives and improving people’s quality of life while protecting the environmen­t to new sectors through novel applicatio­ns and technology.

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