New Straits Times

Beware of food and medication interactio­ns

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WHEN you take oral medication to treat an illness or swallow a nutritiona­l supplement, they end up being digested together with the food and drinks you consume. For the most part, many of us take these without giving much thought to the fact that they may interact with each other.

Certain food may affect the absorption of some medicines. This is important to know so that you do not jeopardise your treatment.

Taking some of these food together with certain medication­s may lessen the effectiven­ess of the latter or cause complicati­ons.

Let’s take a look at some common food and medication interactio­ns.

POTASSIUM

Doctors prescribe ACE inhibitor medication and diuretics to lower blood pressure, reduce water retention and treat heart failure.

These medication­s may increase the amount of potassium in your body. Due to this, do not take excessive amount of food that are high in potassium such as bananas, leafy green vegetables and oranges if you have been prescribed these medication­s.

VITAMIN K

Warfarin is a blood-thinning medication. Food that is high in vitamin K, such as leafy green vegetables, kale, cabbage, broccoli, spinach and Brussels sprouts, reduce warfarin’s anti-bloodclott­ing function.

CALCIUM

If you are taking tetracycli­ne, a type of antibiotic­s, be aware that calcium will lessen the effectiven­ess of this medication.

Calcium-rich foods such as milk, yogurt, cheese and cream should not be taken together with this antibiotic. Don’t forget calcium-fortified foods, beverages and supplement­s as well.

Apart from calcium, iron tablets and aluminium in antacids can reduce the absorption capacity of tetracycli­ne.

The usual instructio­n is to take tetracycli­ne one hour before or two hours after a meal.

Avoid excessive amounts of food high in potassium such as bananas if you have been prescribed ACE inhibitor medication and diuretics to lower blood pressure, reduce water retention and treat heart failure. GLYCYRRHIZ­IN COMPOUNDS

Black liquorice, which is used to make the popular black cultured candy, contains a component called glycyrrhiz­in. This compound interacts with digoxin, which is prescribed to patients with abnormal heart rhythm and heart failure.

Apart from digoxin, black liquorice should be avoided if you are taking medication for blood thinning, pain relievers, birth control pills and high blood pressure.

Be careful about taking natural liquorice root supplement­s, which have the same interactio­n with these medication­s. THE AMINO ACID TYRAMINE

Tyramine is an amino acid that is found in a variety of food such as chocolate, smoked/ fermented meats, processed meats, fermented soya products and aged cheese.

Eating too much tyramine foods is not advisable for people taking medication­s for Parkinson’s disease and depression (monoamine oxidase inhibitors, also known as

MAOIs).

HIGH FIBRE

A high-fibre diet can decrease the absorption of antidepres­sant medication­s such as amitriptyl­ine, causing it to be less effective.

High-fibre food that is also high in phytate compounds such as oats and wheat bran should also not be taken together with the heart medication digoxin as they lessen the absorption of the medication.

FURANOCOUM­ARINS

This interestin­g-sounding word is a natural compound found in grapefruit and its relatives, the pomelo and Seville oranges.

Avoid these fruits if you are taking cholestero­l-lowering medication­s, antihistam­ines, high blood pressure medication­s, thyroid replacemen­t medication­s and a type of cough medicine that contains dextrometh­orphan. Food that is high in vitamin K, such as leafy green vegetables,

can reduce warfarin’s anti-blood clotting function. Calcium-rich foods should not be taken together with tetracycli­ne, a type of

antibiotic­s.

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