The Borneo Post

Simple blood test may reveal your body’s inner clock

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WASHINGTON: Ever feel like it’s 7am, even though the clock says 9am?

A team of researcher­s at Northweste­rn University said Monday they have designed a blood test that can measure a person’s inner body clock within 1.5 hours, an advance that may help personalis­e medical treatments in the future.

The study was published in the Proceeding­s of the National Academy of Sciences ( PNAS), a peer-reviewed US journal.

The ‘circadian rhythm’ governs all cells in the body, and is a burgeoning field of research.

Three US geneticist­s won the Nobel Prize for Medicine last year for discoverin­g the molecules that drive the process.

This biological clock regulates “all sorts of biological processes, when you feel sleepy, when you feel hungry, when your immune system is active, when your blood pressure is high, when your body temp changes,” said lead author Rosemary Braun, assistant professor of biostatist­ics at Northweste­rn University.

When the clock is not regulated properly, research has shown a link to diseases like Alzheimer’s, heart problems and diabetes.

Other research has pointed to the possibilit­y some medical interventi­ons like chemothera­py or blood pressure drugs might be more effective if taken at a certain time.

For the current study, researcher­s took more than 1,100 blood samples from 73 people.

Samples were taken about every two hours, and gene activity was tested at each interval to see how it changed over the course of a day.

The research allowed scientists to decipher if a person’s body clock was off, for example, by up to two hours. — AFP

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