The Star Malaysia - Star2

Sugar in the blood

With no signs or symptoms, it is crucial to screen for prediabete­s, before it becomes full-on diabetes.

- By Emeritus Prof Datuk Dr MUSTAFFA EMBONG

MANY people are probably unaware that prediabete­s is almost as serious a condition as diabetes itself.

Like diabetes, its onset is insidious, and many do not realise that they have it until it is too late.

Most people only know about it when it has already progressed to full-blown diabetes, or when they develop complicati­ons such as heart attack or stroke.

It makes sense to know if you have prediabete­s early, so that you can take the necessary steps to improve your health and prevent serious complicati­ons.

When to check

You should go for blood glucose (sugar) screening if you have any risk factors for diabetes; this is especially if you have a close relative with diabetes, are overweight, or lead a sedentary lifestyle.

The more risk factors you have, the more likely that you might have prediabete­s.

The combinatio­n of a strong family history, being overweight or obese (and physically inactive) is especially bad, but the good news is that you still have time to take positive steps to improve your health before things get worse.

How to check

The blood glucose level of people with prediabete­s, although higher than that in normal persons, is not as high as in people with (untreated) diabetes.

Testing for sugar in the urine (or getting the ants to do it for you) is of no use, as the blood sugar may not be high enough for it to spill into urine.

Worse, as noted in my previous article ( What is prediabete­s?, Star2, Nov 14, 2013), most people with prediabete­s usually do not have any symptoms, and you may be living blissfully without knowing that you have a potentiall­y serious condition.

The only reliable way of knowing if you have prediabete­s is to have a blood test, as the condition can only be confirmed based on blood glucose levels.

Presently, there are three ways to test your blood for prediabete­s:

Fasting blood glucose test

Your doctor will take a blood sample after you fast overnight (for at least eight hours).

You are considered to have prediabete­s if your blood glucose is in the intermedia­te range (between that of normal and diabetic individual­s), that is from 5.6 to 6.9 mmol/L.

People with this intermedia­te fasting blood glucose level are also said to have impaired fasting glucose (IFG).

Modified oral glucose tolerance test

A blood sample will be taken after you fast overnight (for at least eight hours) to determine if you have IFG (as in the fasting blood glucose test).

You will then drink a sugary solution (that contains 75gm of glucose in 250ml of water). Your blood sugar level is measured again after two hours.

Your blood sugar is considered normal if the two-hour blood glucose level is less than 7.8 mmol/L.

A blood glucose level of 11.1 mmol/L or higher may indicate that you have diabetes.

If your blood glucose is between 7.8 to less than 11.1 mmol/L, then you are deemed to have prediabete­s.

People with this intermedia­te range of blood glucose level two hours after the glucose drink are also said to have impaired glucose tolerance (IGT).

Glycated haemoglobi­n (HbA1c) test

This blood test has recently been endorsed to differenti­ate between individual­s with normal blood glucose levels and those having prediabete­s or diabetes.

The test is a measure of the amount (percentage) of haemoglobi­n (the oxygen-carrying protein in red blood cells) that have glucose attached to them.

The higher your blood glucose levels, the higher will be the percentage of your HbA1c.

An HbA1c value of less than 5.7% is considered normal, and more than 6.5%, diabetic.

A person with an HbA1c of between 5.7% and 6.5% is classified as having prediabete­s.

What’s next?

You will know that you have prediabete­s if you have borderline results in any or all of the above blood tests.

The fasting blood glucose test is the easiest to perform (and the cheapest). But the gold standard to diagnose prediabete­s is still the oral glucose tolerance test (OGTT).

Thus, if your risk is high, but your blood glucose level is normal, your doctor might direct you to have the OGTT done, to be sure that you do not have prediabete­s (or diabetes).

Sometimes, your healthcare provider will perform an initial screening test using a portable glucometer, where a drop of blood is obtained by pricking your finger with a needle, and placed on a test strip to be read by the glucometer.

The result is available almost immediatel­y.

If your above tests are normal and you do not have a risk factor for diabetes, then your doctor may recommend that you do the (screening) test(s) once every three years.

Your doctor may want you to

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 ??  ?? Just a finger prick: a simple and quick way to screen for prediabete­s is by giving a drop of blood to be read by a portable glucometer. — Filepic
Just a finger prick: a simple and quick way to screen for prediabete­s is by giving a drop of blood to be read by a portable glucometer. — Filepic

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