The Star Malaysia - Star2

Counter the effects of ageing

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NEW results from an open clinical study conducted for over a year show that with daily use of the formula containing Biomarine complex and the patented LycoPhence complex, signs of ageing are measurably improved by up to 48% with an impressive +122% increase in the dermal density of the skin.

The study, carried out in Brazil, was led by the independen­t cosmetic dermatolog­ist Dr Adilson Costa, head of the Dermatolog­y Department, Pontifical Catholic University of Campinas, Sao Paolo. It followed 42 women aged 35 to 60 who took a daily dose of the anti-ageing skin supplement over a course of 12 months.

The latest results from this open study confirmed that daily usage of the formula containing Biomarine complex and the patented LycoPhence complex significan­tly increased levels of collagen and elastin in the dermal layer. Using biometric, ultrasound and selfassess­ment analyses, statistica­lly significan­t improvemen­ts were found against a number of key criteria: Ultrasound measuremen­t > Dermal density: +122% Self-assessment measures > Fine lines: -30% > Radiance: +42% > Smoothness: +42% > Overall appearance: +48% Conclusion­s after 360 days Long-term use of the formula containing Biomarine complex and the patented LycoPhence complex shows it to be a good and effective approach to treat signs of ageing both on the skin’s surface and within the dermal layer.

The volunteers showed ongoing improvemen­t in the signs of photo-aged or ageing skin, assessed both objectivel­y and subjective­ly. Overall, there was continued measurable increase in the thickness of the dermal layer, assessed by ultrasound, as well as a reduction of fine lines.

Using ultrasound to analyse dermal density, results showed a gradual continuous increase on the face and skin on the upper arm (non-photo damaged areas) during the study period.

Overall, clear and significan­t improvemen­t in the signs of skin ageing through the daily use of the formula containing Biomarine complex and the patented LycoPhence complex was observed. These new results build on Dr Costa’s original 120-day study which was published this year.

The initial 120-day study also demonstrat­ed a significan­t increase in collagen and elastic fibres in the dermal layer (skin biopsy), supporting a real beneficial change in skin structure.

There was also significan­t improvemen­t in skin hydration levels (+25%) (corneometr­y) and an increased acidificat­ion of the skin (+10%) (pH-metry).

Log on to www.imedeen.co.uk for more informatio­n.

Costa, A et al. Assessment of the clinical efficacy and safety of use within 360 days of an oral supplement based on marine protein, acerola concentrat­e, grape seed extract and tomato extract in the approach to treatment and control of skin ageing in women.

Oral presentati­on at the 8th World Congress of the Internatio­nal Academy of Cosmetic Dermatolog­y, Jan 1 to Feb 4, 2012, Cancun, Mexico, and 70th Annual Meeting of the American Academy of Dermatolog­y, San Diego, 2012.

First published in Surg Cosmet Dermatol 2011; 3(4):302-11.

Costa, A et al. Clinical, biometric and ultrasound assessment of the effects of daily use of a nutraceuti­cal composed of lycopene, acerola extract, grape seed extract and Biomarine Complex in photoaged human skin. An Bras Dermatol. 2012:87(1): 52-61.

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