In­no­va­tion in ed­u­ca­tion

The Star Malaysia - Star2 - - COURSE FOCUS -

ALL four Monash Uni­ver­sity Malaysia teams were awarded gold medals at the re­cent 2016 In­ter­na­tional In­ven­tion, In­no­va­tion & Technology Ex­hi­bi­tion ( Itex).

Or­gan­ised by the Malaysian In­ven­tion and De­sign So­ci­ety ( MINDS), the ex­hi­bi­tion aims to cul­ti­vate the abil­ity to think crit­i­cally – a qual­ity sep­a­rat­ing in­no­va­tors from fol­low­ers.

In­ven­tions were judged based on the fol­low­ing cri­te­ria: nov­elty, in­ven­tive­ness, use­ful­ness and ap­pli­ca­tion, pre­sen­ta­tion and demon­stra­tion, mar­ket and com­mer­cial po­ten­tial and en­vi­ron­men­tal friend­li­ness.

The first in­ven­tion was a UV LED ( light- emit­ting diode) mask aligner sys­tem by Dr Narayanan Ramakrishnan and PhD stu­dent Lee Neam Heng from the School of En­gi­neer­ing.

The lithog­ra­phy tech­nique is the driv­ing force in the pat­tern­ing tech­nique, where elec­tronic chips as small as 22nm are pro­duced.

Out of the many lithog­ra­phy tech­niques used in IC ( in­te­grated circuit) fab­ri­ca­tion, UV lithog­ra­phy is one of the most com­mon meth­ods.

A mask aligner is gen­er­ally used for car­ry­ing lithog­ra­phy pro­cesses and the in­vest­ment of the type of set­ups can be quite ex­pen­sive.

In Malaysia, the IC fab­ri­ca­tion in­dus­tries, re­search and de­vel­op­ment in­sti­tu­tions, gov­ern­ment re­search cen­tres and uni­ver­si­ties im­port these ma­chines at a high cost of RM400,000 to RM500,000 for a ba­sic bench- top sys­tem.

With this in­ven­tion of a UV LED lithog­ra­phy mask aligner sys­tem based on solid state light­ing de­vices, pro­duc­tion cost can be as low as RM15,000 to RM20,000, with op­er­a­tional func­tions equiv­a­lent to the state- of- the- art bench- top mask aligner sys­tem.

The sec­ond cre­ation was a world’s first pH- sen­si­tive in­or­ganic nanocrys­tals by As­soc Prof Md Ezharul Hoque Chowdhury from the Jef­frey Cheah School of Medicine and Health Sciences.

To serve as an ef­fi­cient drug trans­porter, this prod­uct is de­signed based on pH- sen­si­tive and biodegrad­able in­or­ganic nanopar­ti­cles that have prop­er­ties of elec­tro­static bind­ing to DNA ( de­oxyri­bonu­cleic acid), siRNA ( small in­ter­fer­ing ri­bonu­cleic acid), pro­teins and small molecule drugs.

It can de­liver a ca­pac­ity across the blood stream and cell mem­brane ef­fi­ciently to ex­ert a ther­a­peu­tic ef­fect.

The third in­ven­tion was an aquatic an­i­mal growth en­hance­ment by Prof Ish­war Parhar, Dr Satoshi Ogawa and Dr Shogo Moriya of the Brain Re­search In­sti­tute Monash Sun­way ( BRIMS).

This project de­vel­ops a new method for the growth en­hance­ment of aquatic an­i­mals with a com­bi­na­tion of two pro­teins – kisspeptin and ghre­lin.

The last was a biodegrad­able poly­mers for drug de­liv­ery and wastew­a­ter treat­ment in­ven­tion by Dr Push­pa­malar Ja­narthanan and Dr Sar­a­vanan Mu­niyandy of the School of Sci­ence and School of Phar­macy.

The in­no­va­tion was based on the con­cept of mod­i­fy­ing polysac­cha­rides in cut­ting- edge strate­gies to cre­ate some­thing, which can po­ten­tially be used in a clin­i­cal set­ting, as well as for fu­ture ap­pli­ca­tion in the bio­med­i­cal and phar­ma­ceu­ti­cal­re­lated drug de­liv­ery sys­tems.

This can be ad­min­is­tered in the gas­troin­testi­nal tract to trans­port anti- can­cer drugs to the tar­geted site ef­fi­ciently.

These hy­dro­gels are able to de­liver anti- can­cer drugs to the tar­geted site without harm­ing nor­mal cells. It also has the abil­ity to en­hance the ther­a­peu­tic ef­fect.

Apart from treat­ing can­cer, with both the swellable and pH- sen­si­tive char­ac­ters, it can also be used to ad­sorb heavy me­tals and dyes from in­dus­trial wastew­a­ter, con­tribut­ing to bet­ter management of wastew­a­ter in the agri­cul­tural in­dus­try.

For more in­for­ma­tion, visit www. monash. edu. my.

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