Cholesterol, statins and CoQ10 – What’s the connection?
ACCORDING to the National Health and Morbidity Survey 2015, 47.7% of Malaysian adults aged above 18 years had a high cholesterol level.
Surprisingly, four out of five sufferers did not know they had high cholesterol
The good news is high cholesterol level can be managed through healthy eating, exercising, losing weight and taking cholesterol lowering medication.
Cholesterol lowering medication – statins are widely known as one of the ways to lower high cholesterol level.
Statins work by reducing the liver’s production of cholesterol. They block an enzyme called HMG CoA reductase that the liver uses to produce cholesterol
In the body, cholesterol and coenzyme Q10 (CoQ10) are produced through the same pathway. When statin blocks the production of cholesterol, it blocks the production of CoQ10 as well. Statin usage can impact on the CoQ10 level as soon as after 14 days of exposure
Present naturally in the body, CoQ10 is mostly found in organs with high-energy demands – heart, liver and kidneys.
CoQ10 is primarily important for energy production and provides antioxidant protection against free radicals. Inhibition of CoQ10 production could explain the reported effects of statins, especially fatigue. Therefore, top up your day with CoQ10 when taking statins for optimum health protection
CoQ10 in the form of ubiquinone is extensively studied since its discovery in 1957. Safety assessment of CoQ10 using method established by FAO/WHO indicates that the observed safe level for CoQ10 is 1,200mg/day
There is no specific CoQ10 recommendation for everyone. Daily requirement is based on many factors, including body conditions, medical history and age.
CoQ10 supplementation is used in different health conditions at various dosages
At 300mg, CoQ10 helps improve antioxidant capacity and reduce inflammation among statin users
StemLabs CoQ10 300mg (MAL 16085008NCR), is manufactured in New Zealand and offers high strength of CoQ10 at one a day capsule in ubiquinone form.
In addition, StemLabs CoQ10 300mg helps to:
– Improve energy and stamina – Reduce fatigue
– Promote physical performance and faster recovery This article is brought to you by Cellgen Lifesciences (M) Sdn Bhd
References
National health and morbidity survey 2015 (NHMS 2015). Vol.II: non-communicable diseases, risk factors & other health problems.
Tatjana R., Ali N., Ralph S., Kristen C. & Salvatore D. 2004. Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke. Arch Neurol 61: 889-892.
Lee et al. 2013. Effects of coenzyme Q10 supplementation (300mg/day) on antioxidant and anti-inflammation in coronary artery disease patients during statins therapy: a randomized, placebo controlled trials. Nutrition Journal 12:142.
Hathcock & Shao. 2006. Risk assessment for coenzyme Q10 (Ubiquinone). Regulatory Toxicology and Pharmacology 45(3): 282-288.
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