The Sun (Malaysia)

Antioxidan­ts can beat colon cancer

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A STUDY, published recently by the Journal of Cancer, has revealed the therapeuti­c effects of two antioxidan­t compounds when combined to fight colon cancer.

Curcumin is the active ingredient in turmeric ( above), already known for its antiinflam­matory properties, whereas silymarin, a component of milk thistle, has been used to treat liver disease.

In laboratory tests, researcher­s from Saint Louis University in the US found that colon cancer cells stopped multiplyin­g and spreading, and that cell death increased when exposed to the two natural compounds.

When exposing colon cancer cell cultures to curcumin – the polyphenol that gives curry dishes their bright yellow colour – and then to silymarin, found in the milk thistle plant, researcher­s saw beneficial effects from this pair of natural extracts.

The scientists found that the combinatio­n of these two natural compounds stopped the multiplica­tion of cancer cells and increased cell death.

Several previous studies have highlighte­d the beneficial properties of curcumin, such as its anti-inflammato­ry nature, its ability to lower triglyceri­de levels or its capacity to boost cognitive health by combatting Alzheimer’s and Parkinson’s disease.

The compound’s anti-cancer properties have previously been observed in breast cancer and prostate cancer research.

Silymarin is a component of milk thistle – a plant of the Asteraceae family – which is beneficial to the liver.

In 1989, the European Commission approved the use of a standardis­ed concentrat­ion of 70-80% of silymarin in the treatment of toxic liver damage and for supportive treatment in chronic inflammato­ry liver disease and hepatic cirrhosis.

In 2002, the World Health Organisati­on recognised similar uses.

The scientists’ discovery reveals a promising alternativ­e approach to standard colon cancer treatments, avoiding problems with toxicity and side effects. Still, further testing is required. – AFP-Relaxnews

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