The Sun (Malaysia)

Fat-burning exercise can boost bone health

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NEW research on animals has found for the first time that exercise can help to improve bone health by burning off the fat found within bone marrow.

Carried out by the University of North Carolina School of Medicine in the US, the study looked at two groups of mice, a lean group which was fed a normal diet, and an obese group which was fed a high-fat diet starting a month after birth.

When they were four months old, half the mice in each group were given a running wheel to use whenever they wanted for the next six weeks.

At various points during the study, the team analysed the animals’ body compositio­n, marrow fat and bone quantity.

As expected, the results showed that the obese group started with more fat cells and larger fat cells in their bone marrow.

However, after the six weeks, both the obese and lean mice who had exercised on the wheel showed a significan­t reduction in the overall amount fat, and overall size of fat cells.

In fact, when looking at these two factors, the marrow fat of exercising obese mice was virtually identical to the marrow fat of lean mice, even those that had exercised.

The team also found that while the lean mice showed no difference in the number of fat cells in the marrow, exercising obese mice showed more than a 50% drop in these fat cells, compared to obese mice that were sedentary.

Exercising obese mice also showed greater improvemen­ts in bone thickness than the exercising lean mice.

According to lead author Maya Styner, the findings suggest exercise can burn off marrow fat, building stronger, larger bones, which could be of particular importance to those with obesity who often have poorer bone quality.

“With obesity, it seems that you get even more bone formation from exercise,” adds Styner. “Our studies of bone biomechani­cs show that the quality and the strength of the bone is significan­tly increased with exercise and even more so in the obese exercisers.”

Although the findings in mice are not directly translatab­le to humans, the stem cells that produce bone and fat in mice are the same kind as in humans. – AFP-Relaxnews

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