Malta Independent

Scientists appeal for more people to donate their brains

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Scientists are appealing for more people to donate their brains for research after they die.

They say they are lacking the brains of people with disorders such as depression and post-traumatic stress disorder.

In part, this shortage results from a lack of awareness that such conditions are due to changes in brain wiring.

The researcher­s’ aim is to develop new treatments for mental and neurologic­al disorders.

The human brain is as beautiful as it is complex. Its wiring changes and grows as we do. The organ is a physical embodiment of our behaviour and who we are.

In recent years, researcher­s have made links between the shape of the brain and mental and neurologic­al disorders.

More than 3,000 brains are storied at the Harvard Brain Tissue Resource Centerat McLean Hospital just outside Boston. It is one of the largest brain banks in the world.

Most of their specimens are from people with mental or neurologic­al disorders.

Samples are requested by scientists to find new treatments for Parkinson’s, Alzheimer’s and a whole host of psychiatri­c disorders.

But there is a problem. Scientists at McLean Hospital and at brain banks across the world do not have enough specimens for the research community.

According Dr Kerry Ressler, who is the chief scientific officer at McLean hospital, new treatments for many mental and neurologic­al diseases are within the grasp of the research community. However, he says it is the lack of brain tissue that is holding back their developmen­t.

“We have the tools and the ability to do some great deep-level biology of the human brain now.

“What we are lacking are the tissues from those with the disorders we need to really understand.”

One donor visiting the hospital, who wished to be known only as Caroline, said that she decided to donate her brain for medical research partly because her sister has schizophre­nia.

She hopes that her donation will help researcher­s find a cure – and she’s urging others to do the same.

“My parents were fine but why did my sister get schizophre­nia? We are not sure where it came from. How are we going to find out if we don’t do the research on the brain, which is where the problem is.”

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