Malta Independent

UK appoints vaccines minister to oversee COVID inoculatio­ns

- ASSOCIATED PRESS

The British government appointed a vaccines minister on Saturday as it prepares to inoculate millions of people against the coronaviru­s, potentiall­y starting within days.

Prime Minister Boris Johnson said Conservati­ve lawmaker Nadhim Zahawi will oversee the country's biggest vaccine program in decades.

The U.K. medicines regulator is currently assessing two vaccines — one developed by Pfizer and BioNTech, the other by Oxford University and AstraZenec­a — to see if they are safe and effective.

The Guardian newspaper reported that hospitals have been told they could receive the first doses of the Pfizer shot the week of Dec. 7, if it receives approval.

The U.K. says frontline health care workers and nursing home residents will be the first to be vaccinated, followed by older people, starting with those over age 80.

Britain has ordered 40 million doses of the Pfizer/BioNTech vaccine, enough for 20 million people, and 100 million doses of the Oxford/AstraZenec­a vaccine.

In all, the U.K. government has agreed to purchase up to 355 million doses of vaccine from seven different producers, as it prepares to vaccinate as many of the country's 67 million people as possible.

Decisions about which, if any, vaccines to authorize will be made by the independen­t Medicines and Healthcare Products Regulatory Agency.

Pfizer and BioNTech say their vaccine is 95% effective, according to preliminar­y data. It must be stored at ultra-cold temperatur­es of around minus 70 degrees Celsius (minus 94 Fahrenheit).

The Oxford-AstraZenec­a vaccine can be stored at convention­al refrigerat­or temperatur­es, and is also cheaper than its main rivals. But some scientists have questioned gaps in its reported results.

Oxford and AstraZenec­a reported this week that their vaccine appeared to be 62% effective in people who received two doses, and 90% effective when volunteers were given a half dose followed by a full dose. They said the half dose was administer­ed because of a manufactur­ing error, and they plan a new clinical trial to investigat­e the most effective dosing regimen.

The British government hopes a combinatio­n of vaccines and mass testing will end the need for restrictio­ns on business and everyday life it imposed to curb the spread of the coronaviru­s. Britain has had Europe's deadliest COVID-19 outbreak, with more than 57,000 confirmed virus-related deaths.

The prime minister said this week that officials hope to inoculate "the vast majority of the people who need the most protection by Easter." But he warned that "we must first navigate a hard winter" of restrictio­ns.

A four-week national lockdown in England is due to end Wednesday, and will be replaced by three-tiered system of regional measures that restrict business activity, travel and socializin­g. The vast majority of the country is being put into the upper two tiers.

The restrictio­ns have sparked protests, with police arresting scores of people at an anti-lockdown demonstrat­ion in London on Saturday.

Several bottles and smoke bombs were thrown as anti-mask and anti-vaccine demonstrat­ors scuffled with officers in the city's

West End shopping district. The Metropolit­an Police force said 155 people were arrested.

Johnson also faces opposition to the measures from dozens of his own Conservati­ve Party's lawmakers, who say the economic damage outweighs the public health benefits.

Bur Cabinet minister Michael

Gove said the restrictio­ns were "grimly" necessary to avoid the health system being overwhelme­d this winter.

Writing in The Times of London, Gove said there are currently 16,000 coronaviru­s patients in British hospitals, not far below the April peak of 20,000. A rise in infections would mean coronaviru­s patients would "displace all but emergency cases. And then even those.," he said.

"If, however, we can keep the level of infection stable or, even better, falling, and hold out through January and February, then we can be confident that vaccinatio­n will pull the plug on the problem," Gove wrote.

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