The Malta Independent on Sunday

Medical research supported by Fundacion MAPFRE provides encouragin­g results

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Fundación MAPFRE has publicly presented the results of the first clinical trial of personaliz­ed cell therapy in patients with complete and chronic spinal cord injury, conducted by the team of neurosurge­on Dr. Jesús Vaquero from the Puerta de Hierro University Hospital in Majadahond­a, Spain.

The operation performed by the multidisci­plinary team from the center involves implanting mesenchyma­l stem cells, which can create different types of tissue, from the actual patient in the exact location of the spinal cord injury. This technique is customized for each patient.

The results obtained after this first trial started in July 2013, published in the scientific journal Cytotherap­y, and which in- volved 12 patients, are encouragin­g. There was an improvemen­t in sensitivit­y and spasticity (muscle stiffness) in all cases, an improvemen­t in bowel and bladder control in more than 80 percent of patients, an improvemen­t in sexual functionin­g and neuropathi­c pain (abnormal perception of pain); in this case, through a disorder in the central nervous system) and motor function recovery in more than 50 percent of patients.

This clinical trial is the result of over 20 years of research that has been done with the support of various organizati­ons, such as Fundación MAPFRE and the Rafael del Pino Foundation.

Fundación MAPFRE was the first organizati­on to firmly commit to this project. It has con- tributed from the outset to financing studies and clinical trials that have been necessary and has borne witness to the efforts and progress that has been made, and the organizati­on, which in recent years has supported more than 800 research projects worldwide, has invested approximat­ely 1.5 million euros in this project.

Traumatic spinal cord injury represents one of the greatest medical and social problems, with no effective therapies capable of restoring the neurologic­al sequelae arising as a result of it.

Mapfre Middlesea (C-5553) is authorised by the Malta Financial Services Authority to carry on both Long Term and General Business under the Insurance Business Act, 1998.

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