Manawatu Standard

Prince died with lethal fentanyl throughout body

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UNITED STATES: A toxicology report from Prince’s autopsy shows the singer had what multiple experts called an ‘‘exceedingl­y high’’ concentrat­ion of fentanyl in his body when he died.

Prince was

57 when he was found alone and unresponsi­ve in an elevator at his Paisley Park estate on April 21, 2016.

Public data released six weeks after his death showed he died of an accidental overdose of fentanyl, a synthetic opioid 50 times more powerful than heroin.

A confidenti­al toxicology report provides some insight into just how much fentanyl was in his system.

Experts who are not connected to the Prince investigat­ion said the numbers leave no doubt that fentanyl killed him.

‘‘The amount in his blood is exceedingl­y high, even for somebody who is a chronic pain patient on fentanyl patches,’’ said Dr Lewis Nelson, chairman of emergency medicine at Rutgers New Jersey Medical School.

He called the fentanyl concentrat­ions ‘‘a pretty clear smoking gun’’.

The report says the concentrat­ion of fentanyl in Prince’s blood was 67.8 micrograms per litre. The report explains that fatalities have been documented in people with blood levels ranging from three to 58 micrograms per litre.

The report also says the level of fentanyl in Prince’s liver was 450 micrograms per kilogram, and notes that liver concentrat­ions greater than 69 micrograms per kilogram ‘‘seem to represent overdose or fatal toxicity cases’’.

There was also what experts called a potentiall­y lethal amount of fentanyl in Prince’s stomach.

Dr Charles Mckay, president of the American College of Medical Toxicology, said generally speaking, the findings suggest Prince took the drug orally, while fentanyl in the blood and liver suggest it had some time to circulate before he died.

Experts say there is no ‘‘lethal level’’ at which fentanyl can kill. A person who takes prescripti­on opioids for a long time builds up a tolerance, and a dose that could kill one person might help another.

Search warrants released about a year after Prince’s death showed authoritie­s found numerous pills in various containers around his home. A lab report showed many of the pills tested positive for fentanyl and other drugs.

Informatio­n that has been released publicly indicates the source of those drugs hasn’t been determined. –AP

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