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Psychology

Hypothermi­a kills, but it can be a lifesaver for people with brain injuries.

- By Marc Wilson

Hypothermi­a kills, but it can be a lifesaver for people with brain injuries.

It’s easy to believe that Wellington holds the crown for the most reliably dry Christmas in New Zealand. Niwa said so. Admittedly, it also said Wellington shared the honour with Christchur­ch, but I shall take what I can get.

Yesterday, however, I saw snow. But this was because I am in Boston. Today’s high was a balmy 3°C, but on New Year’s Day it got down to -10°C, with blizzard conditions. There are piles of snow on the footpaths, the Charles River has iced over and people are skating on Frog Pond.

However, it’s a far cry from the coldest winters on Earth. On the Antarctic coast, the temperatur­e drops to below -40°C and in the depths of winter it hits below -80°C. Talk about chilly.

Humans are not designed to cope with extreme cold. More than a thousand people die from hypothermi­a each year in the US, and although New Zealand’s rates are harder to find, it’s probably a couple of dozen a year.

Unsurprisi­ngly, our hearts and brains are particular­ly sensitive to the effects of the cold, and because they’re quite important, we want to keep them warm. One of the things our bodies try to do when the temperatur­e drops is divert blood from lessimport­ant extremitie­s to our vital organs.

Temperatur­e regulation is part of the job of the hypothalam­us, when it’s not looking after other basic physiologi­cal processes such as hunger, thirst, sleep and libido. If our core temperatur­e continues to drop, the electrical activity in our hearts and brains does too, and organs start to fail.

Normal human body temperatur­e is about 37°C, but if you’ve had kids (or a fever), you know it doesn’t take much of a deviation from that for us to start worrying. Hypothermi­a starts when our internal temperatur­e drops below 35°C. The heart starts to become erratic at around 28°C, and at 20°C … well, the brain will take a rest.

Long before that point, though, we get rather less good at stuff – mild hypothermi­a comes with such neurologic­al effects as dizziness and difficulty with speech and co-ordination. If we get colder, expect slurred speech, confusion and apathy – no longer caring.

Hypothermi­a has some uses, though, or at least mild hypothermi­a does. Lowering core temperatur­e under controlled conditions is now a common way to improve outcomes for acute brain-injury sufferers. Deliberate therapeuti­c hypothermi­a, or “target temperatur­e management”, has been around for more than 70 years but has become almost standard since the early 2000s, because randomised studies showed that dropping core temperatur­e to 33°C for up to a day improved the end result.

This is because, as well as the bad stuff that can happen, hypothermi­a reduces brain energy load and the associated mechanisms involved and reduces the inflammati­on that usually accompanie­s a brain injury.

The heart starts to become erratic at 28°C, and at 20°C the brain will take a rest.

As a result, the brain gets a rest and doesn’t back up with juices as much.

This last is particular­ly important, because excessive pressure of cerebrospi­nal fluid on the brain (or intracrani­al hypertensi­on) is one of the biggest predictors of brain-injury outcomes.

This presents me with the tricky decision of whether to go ice skating. The US has about 2000 skating-related head injuries annually. The upside is that it will be cold.

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