The New Zealand Herald

WHO issues warning over superbugs

Health officials say nations need to take action as bacteria build resistance to drugs

- Sarah Knapton

Superbugs which cause sepsis, pneumonia, and salmonella will soon be resistant to antibiotic­s, the World Health Organisati­on has warned as it called on government­s to stop relying on pharmaceut­ical companies to solve the crisis.

Health officials have drawn up a list of 12 types of bacteria which pose the “greatest threat to human health” because soon no drugs will be able to fight them off.

Experts have previously warned that resistance to the drugs that are used to fight infections could cause a bigger threat to mankind than cancer.

If antibiotic­s lose their effectiven­ess, key medical procedures — including organ transplant­ation, caesarean sections, joint replacemen­ts and chemothera­py — could become too dangerous to perform.

Around 700,000 people around the world die annually due to drugresist­ant infections and, if no action is taken, it has been estimated that such infections will kill 10 million people a year by 2050.

Now, the WHO has come up with a list of antibiotic-resistant “priority pathogens” — 12 families of bacteria that pose the greatest threat to human health.

Medical research charity the Wellcome Trust said that the list was important to steer research into new antibiotic­s.

The bacteria on this list can cause severe and often deadly infections such as bloodstrea­m infections and pneumonia and the most critical group includes multi-drug-resistant bacteria that pose a particular threat in hospitals and nursing homes.

Other increasing­ly drug-resistant bacteria, which are deemed “high” and “medium” priority, cause more common diseases such as gonorrhoea and food poisoning — caused by salmonella.

“Antibiotic resistance is growing and we are fast running out of treatment options,” said Dr Marie-Paule Kieny, WHO’s assistant directorge­neral for health systems and innovation.

“If we leave it to market forces alone, the new antibiotic­s we most urgently need are not going to be developed in time.”

The WHO said that it hoped the list would spur government­s to put in place policies to incentivis­e the developmen­t of new drugs.

Experts came up with the list by examining a number of criteria, including how deadly the infections the bacteria cause are and whether new antibiotic­s to treat them are already in the pipeline.

Commenting on the publicatio­n of the list, Tim Jinks, head of drug resistant infections at Wellcome Trust, said: “This priority pathogens list, developed with input from across our community, is important to steer research in the race against drugresist­ant infection — one of the greatest threats to modern health.

“Without effective drugs, doctors cannot treat patients.

“Within a generation, without new antibiotic­s, deaths from drugresist­ant infection could reach 10 million a year.

“Without new medicines to treat deadly infection, life-saving treatments like chemothera­py and organ transplant, and routine operations like caesareans and hip replacemen­ts will be potentiall­y fatal.

“Wellcome is committed to helping tackle this growing problem, guided by WHO priorities.”

If we leave it to market forces alone, the new antibiotic­s we most urgently need are not going to be developed in time. Dr Marie-Paule Kieny

 ?? Picture / AP ?? Treating salmonella infections could become harder as it builds resistance to antibiotic­s.
Picture / AP Treating salmonella infections could become harder as it builds resistance to antibiotic­s.

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