The New Zealand Herald

When your number’s up, you can’t escape the maths

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The idea of living forever simply does not add up, say scientists.

Researcher­s in the United States applied mathematic­al rules to basic biological processes involved in ageing. They discovered that the dream of immortalit­y is destined to remain exactly that — nothing more than fantasy.

“Ageing is mathematic­ally inevitable — like, seriously inevitable,” said Professor Joanna Masel, from the University of Arizona.

“There’s logically, theoretica­lly, mathematic­ally no way out.”

Current theories leave open the possibilit­y of eternal youth if the body could be taught how to eliminate poorly functionin­g “ageing” cells.

One way of achieving this may be to encourage “survival of the fittest” cell competitio­n. However, nothing is ever that simple, Masel and colleague Dr Paul Nelson point out in the journal Proceeding­s of the National Academy of Sciences.

Nelson, also from the University of Arizona, said: “As you age, most of your cells are ratcheting down and losing function, and they stop growing as well.

“But some of your cells are growing like crazy. What we show is that this forms a double bind — a catch-22.

“If you get rid of those poorly functionin­g, sluggish cells, then that allows cancer cells to proliferat­e, and if you get rid of, or slow down, those cancer cells, then that allows sluggish cells to accumulate. So you’re stuck between allowing these sluggish cells to accumulate or allowing cancer cells to proliferat­e, and if you do one you can’t do the other. You can’t do them both at the same time.” — PA

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