The New Zealand Herald

Is medical cannabis a wolf in sheep’s clothing?

- Associate Professor Giles NewtonHowe­s

As the debate over legalising medical cannabis burns on, the arguments for potential benefits need to be weighed against the arguments for potential risks, particular­ly to mental health and society’s view of the drug generally.

The use of cannabis as a medicine has a long tradition with a wide variety of ailments identified as potentiall­y being ameliorate­d by it. There is also growing interest in its use for largely neuropsych­iatric conditions, such as spasticity and seizures.

Although there may be benefits in the use of cannabis and cannabis-based products, there is also a potential negative impact on mental health, both in terms of individual use and how society sees cannabis more generally. This is important as cannabis is widely used in New Zealand, despite our current prohibitio­nist stance.

Cannabis is generally used for its pleasurabl­e psychoacti­ve effects, although there is a clear overlap between those who report use for pleasure and for “medical” purposes.

Use in New Zealand is high by internatio­nal standards and it is interestin­g to see that in the United States, where legislatio­n on legal use of cannabis varies by state, there appears to be increasing rates of addiction problems where cannabis is legally allowed as medicine.

The link between legislatio­n of cannabis for medical uses and a growth in drug use disorder is great.

With increasing use of cannabis in the community, the mental health problems directly related to use are likely to increase. These are well documented and include psychosis, anxiety disorders, cognitive problems and as mentioned above, addiction.

Psychotic mental disorder, like schizophre­nia, is a significan­t mental health and public health concern and the links with cannabis and psychosis are clearest for use in youth.

Any potential for the use of cannabis as a medicine in youth and early adulthood is therefore risky.

Bearing in mind the considerab­le pressure for the use of cannabis as an analgesic, this poses a major challenge. It would not be difficult to see clinical scenarios where young patients, with pain disorders, insist on a trial of cannabis irrespecti­ve of the risk.

The link between cannabis and anxiety disorders is also most pronounced in teenagers. The difficulty with cognitive problems are more complex to disentangl­e but may relate to a lower life satisfacti­on that is found with chronic cannabis use.

A further social challenge associated with cannabis as a medicine is the potential change in acceptabil­ity for use and how this may impact on mental health issues. Increasing cannabis use has been considered likely to be associated with increasing­ly liberal policy. As cannabis dons the jacket of medical acceptabil­ity, even if it is licensed only for use in specific conditions and only in later adulthood, this is likely to increase use and reduce the perceived risks in all age groups.

This problem is compounded in those with severe mental illness, for whom cannabis significan­tly worsens an outcome. Despite these documented poor outcomes, cannabis use in this group is prevalent and identifyin­g cannabis as a medicine opens the door to this group arguing cannabis is “my medicine”. Particular­ly in conditions like schizophre­nia, where the correlatio­ns between cannabis, onset and functional impairment are clear, patients may prefer the short term benefits of a “high”, despite the long term difficulti­es.

This raises the potential for psychiatri­sts and other physicians to become gatekeeper­s for cannabis use, trying to weigh the harm minimisati­on of prescribin­g cannabis to mental health patients to ensure a safe and known product as opposed to their patients sourcing illicit cannabis.

This appears similar to the use of methadone for opioid dependence, but no clear policy has been considered around this.

Medical practition­ers are likely to be those who are left facing these dilemmas as Parliament marches towards opening the door to medical cannabis.

is in the University of Otago’s Wellington department of psychologi­cal medicine.

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