The New Zealand Herald

DNA path may not lead to ancestors

- Bill Keir is an independen­t writer and researcher. Bill Keir comment

Having your DNA tested for informatio­n about your ancestry seems to be the latest fad. Buyer beware. It is not very useful for ancestry research except as supplement­ary informatio­n to confirm what you already know.

It is very accurate for close relationsh­ips such as parent-child, grandparen­t-grandchild and first cousins, but most people already know the identity of these relatives. It is useful and accurate for adopted people who don’t know the identity of their birth parents and want help to find out. They will need tailormade DNA tests and preferably some prior knowledge of likely parents from whom a DNA sample can be obtained.

The standard DNA test offered by ancestry research companies is the autosomal test, which examines chromosome­s 1-22 (the autosomes) and the X-chromosome. This gives you percentage­s of your ancestry by broad geographic­al regions. These state the approximat­e percentage­s of your DNA markers inherited from each region by comparing the frequency of your autosomal DNA markers with those of others in the various population groups.

This is done by computer searches for matches between your autosomal DNA and the autosomal DNA of millions of others on the database. Given that most individual­s on the database are people still alive, this is informatio­n about distant cousins, not distant ancestors.

First cousins share grandparen­ts, second cousins share great-grandparen­ts, third cousins share great-greatgrand­parents, and so on. Nearly all people from a defined geographic­al location alive today are about 13th cousins.

The best that can be said about these DNA ancestry percentage­s by geographic­al location is that they give you informatio­n about your ancestry indirectly from informatio­n about your cousins, and only in approximat­e terms. The percentage­s don’t tell you how distant is the identified common ancestry from the stated region.

Autosomal DNA matches cannot identify individual ancestors by name in the remote past. They can identify recent ancestors and close cousins individual­ly, but most of us already know their identity. Autosomal percentage­s by geographic region can also provide informatio­n about ethnicity, with the same limitation­s.

The percentage­s of your DNA inherited from geographic­al regions tell you little more than you could have guessed. For example, if your grandparen­ts or greatgrand­parents came from UK/Ireland it is highly likely some forebears came from Europe and Scandinavi­a because of regular travel for thousands of years. A result such as, “30 per cent French/ German, 20 per cent British/Irish, 10 per cent Scandinavi­an” can’t be surprising.

The percentage­s will be less accurate the more distant the ancestry. This is because you inherit about half your DNA markers from each parent, a quarter from your four grandparen­ts, an eighth from your eight great-grandparen­ts, and so on.

As little as eight generation­s prior to yourself the proportion of your DNA received from those ancestors will be minuscule and possibly missed in the database search for matches. The markers from that distance may not even exist in your DNA because inheritanc­e is more random from more distant ancestors.

Only 10 generation­s back, you have more than 1000 direct ancestors from whom you get a little of your DNA. Percentage­s by geographic­al region are not enlighteni­ng about all these ancestors, and pretty useless beyond 10 generation­s.

The autosomal test results by geographic­al region are said to be too inaccurate beyond eight generation­s prior to yourself. Other types of test can be more accurate than this for some purposes. For example, the mitochondr­ial DNA test is said to be accurate to 50 generation­s prior to yourself, but only along the female lines because this DNA passes from mother to child with few modificati­ons.

The autosomal tests cannot identify markers of inherited diseases or specific inherited physical traits. For these you need other test types that cost more.

Specific tests for adopted people to confirm parent-child relationsh­ips are usually very accurate, giving 95 per cent probabilit­y that two individual­s are parent and child, or 95 per cent probabilit­y they are not. These tests preferably need a DNA sample from both and examine the matching markers in the X- and Y-chromosome­s or the mitochondr­ial DNA in females.

This feature of DNA testing — its accuracy for close relationsh­ips — is also useful for matching DNA at a crime scene with a suspect.

DNA tests for ancestry are expensive. You would be better to spend that money on a subscripti­on to the ancestry research company’s service giving online access to a large range of civil and parish records. These, however, are only as accurate as the informatio­n provided by the original informant, and tracing a lineage can become error-prone the more distant the ancestry. But at least you get a person’s name that you could verify by other means. And they will be more use to your ancestry research than approximat­e percentage­s by geographic regions that tell you what you already know, or have guessed. Companies promoting DNA tests for ancestry seldom explain the limitation­s. They want your money.

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