The Timaru Herald

Sharks threatened by hunt for virus vaccine

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Sharks face being slaughtere­d for the coronaviru­s vaccine, as conservati­onists warn as many as half a million could be killed for global supplies.

One of the ingredient­s in some versions of the Covid-19 vaccine under developmen­t is squalene, which comes from the livers of sharks.

Scientists are racing to test a synthetic version, made from fermented sugar cane, which would mean plentiful supplies without threatenin­g shark population­s.

Conservati­onists estimate that more than three million sharks are killed each year to obtain their liver oil for various uses, including in cosmetics and machine oil, and fear a sudden rise in demand could push some species closer to the brink.

Squalene from sharks is used in medicine as part of an adjuvant – an ingredient that makes a vaccine more effective and

creates a greater immune response.

British pharmaceut­ical company GlaxoSmith­Kline uses shark squalene in its adjuvant, which is used in flu vaccines. In May GSK said it would manufactur­e a billion doses of this adjuvant for potential use in Covid-19 vaccines.

Around 3000 sharks are required to make 1 ton of squalene. Estimates from California-based group Shark Allies suggest that immunising everyone in the world with one dose of a Covid-19 vaccine containing squalene would require around 250,000 sharks, depending on the quantities used. This doubles to half a million if two doses are required, as researcher­s say is likely.

Many of the species targeted for being rich in squalene, such as the gulper shark and basking shark, are classed as vulnerable, meaning their population­s are decreasing and they could become endangered.

Stefanie Brendl, founder and executive director of Shark Allies, said: ‘‘Harvesting something from a wild animal is never going to be sustainabl­e, especially if it’s a top predator that doesn’t reproduce in huge numbers. There’s so many unknowns of how big and how long this pandemic might go on, and then how many versions of it we have to go through, that if we continue using sharks, the numbers of sharks taken for this product could be really high, year after year after year.’’

Silicon Valley company Amryis has produced synthetic squalene for cosmetics for years, but is hoping to apply its technology to remove the reliance on shark fishing in the vaccine industry. – Telegraph Group

 ??  ?? A grey reef shark swims in tropical waters. It is one of many species hunted for the squalene contents of its liver.
A grey reef shark swims in tropical waters. It is one of many species hunted for the squalene contents of its liver.

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