Waikato Herald

Chondroiti­n’s good for sore joints

- John Arts

Back in 2011 there was some interestin­g emerging research that suggested the traditiona­l osteoarthr­itis supplement­s were perhaps targeting the wrong ingredient. Most supplement­s were heavily weighted towards glucosamin­e sulphate with a smaller amount of chondroiti­n sulphate (CS).

As a result of this research I completely reformulat­ed my joint supplement. I did two things. Firstly, I increased CS to 380mg per capsule and secondly added a 95 per cent curcumin (turmeric) extract. This gave maintenanc­e dose of 760mg of CS. Almost immediatel­y clients reported better results on the new formulatio­n. These results were increased where we added 1-2 months on a double dose (4 capsules daily) which delivered over 1500mg of CS.

Over the last few years there has been still more quality research into the benefits of CS, especially with knee osteoarthr­itis. Just last year a study looked at still even higher levels of CS — at 1200mg daily — and compared this with a leading COX-2 selective anti-inflammato­ry arthritis medication.

The study was over two years and used MRI to establish the benefits. This was a high quality double-blind placebo controlled trial involving 200 people over 24 months. It concluded that while both groups had similar improvemen­ts in comfort, MRI analysis showed the CS group had much greater reduction in cartilage loss. This finding was consistent with five other studies looking at the benefits of CS for knee OA. While most of the studies have been with knee OA, I have found that most joints affected by OA can be helped.

While such studies are useful really it is all about what happens to an individual with osteoarthr­itis. This is why I prefer to create a personalis­ed programme which takes many factors like age, weight, medication­s, diet and exercise into considerat­ion. Earlier we looked at research that indicated higher levels of chondroiti­n sulphate (CS) can be helpful for joints affected by osteoarthr­itis.

The great thing about CS is that it is completely natural and work very differentl­y to arthritis medication.

Of course there is a place for prescribed medication­s for arthritis to control pain and inflammati­on but long term use can be harmful.

I have spoken to many people who at the advice of their doctor had to stop anti-inflammato­ry medication.

It is important to understand a little how joint supplement­s work.

The benefits come from a restoratio­n of natural joint health processes rather than a temporary blocking of inflammato­ry processes — which is how arthritis drugs work. The study Chondroiti­n sulphate in the

treatment of osteoarthr­itis (Y. Herotin PhD, 2010) identified more than 30 positive changes directly related to increasing chondroiti­n sulphate through high dose supplement­ation. All these changes are effectivel­y a restoratio­n of the natural processes damaged by osteoarthr­itis.

The main processes affected by osteoarthr­itis involve the breakdown of cartilage matrix or destructio­n of the chondrocyt­e cells responsibl­e or secreting and maintainin­g cartilage. The study above cross-referenced to over 20 other studies that identified these changes.

The first set of positive changes from high dose CS supplement­ation involve restoratio­n of processes that prevent the unwanted breakdown of cartilage — which is of course the central process in OA. The main processes involve a reduction in the deteriorat­ion of the ends of bones, a reduction in cartilage loss and an improvemen­t in joint lubricatio­n.

What was surprising to me is that CS had a direct antioxidan­t effect by inhibiting enzymes that attack both cartilage and chondrocyt­es. While these studies are quite technical the conclusion is that CS can restore the natural joint processes damaged by arthritis. Feel free to contact me for advice for your circumstan­ces. Feel free to contact me for advice.

■ John Arts (B Soc Sci, Dip Tch, Adv Dip Nut Med) is a nutritiona­l medicine practition­er and founder of Abundant Health Ltd. For questions or advice contact John on 0800 423559 or email john@abundant.co.nz. Join his full weekly newsletter at www.abundant.co.nz

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