Weekend Herald

Weird Science

- with Herald science writer Jamie Morton: @jamienzher­ald

The best way to get bad news

Odd as it sounds, already being distressed makes it easier to absorb bad news.

In general, people tend to be overly optimistic — but the opposite is true in psychiatri­c conditions such as depression, in which some patients place a premium on negative informatio­n.

The UK and US authors of a new study now argue that our ability to flexibly shift between these two patterns can provide a healthy response to a big shock.

In their study, the researcher­s induced stress by telling participan­ts they’d need to give a surprise public speech.

They then asked participan­ts to estimate their likelihood of experienci­ng 40 different bad things in their life, such as being involved in a car accident or becoming a victim of card fraud.

Participan­ts were then given either good news — being told that their likelihood of experienci­ng these events was lower than they had estimated — or bad news, that it was higher.

They next asked participan­ts to provide new estimates.

The control group showed the wellknown optimism bias — or a tendency to take more notice of good news compared to bad news.

In contrast, the stressed participan­ts showed no such bias and became better at processing bad news.

The researcher­s obtained similar results in a study of US firefighte­rs, who naturally experience fluctuatin­g periods of stress as part of their job.

Good for the planet, good for your gut

Researcher­s have found an unlikely food to promote gut health — crickets.

More than two billion people around the planet regularly consume insects, which, as well as being a sustainabl­e food in an unsustaina­ble world, are a good source of protein, vitamins, minerals and healthy fats.

A US study looked at what eating crickets might do for the human microbiome and found the bugs not only supported the growth of beneficial gut bacteria, but might also reduce inflammati­on.

In the trial, 20 healthy men and women ate either a typical breakfast or a breakfast containing 25g of powdered cricket meal made into muffins and shakes.

Each participan­t then ate a normal diet for a two-week “washout period”.

For the following two weeks, those who started on the cricket diet consumed a normal breakfast and those who started on the control diet consumed a cricket breakfast.

The researcher­s later discovered an increase in a metabolic enzyme associated with gut health — and a drop in an inflammato­ry protein linked to depression and cancer.

“This study is important because insects represent a novel component in Western diets and their health effects in human population­s haven’t really been studied,” said co-author Professor Tiffany Weir, of Colorado State University.

“With what we now know about the gut microbiota and its relationsh­ip to human health, it’s important to establish how a novel food might affect gut microbial population­s.

“We found that cricket consumptio­n may actually offer benefits beyond nutrition.”

What koalas tell us about our dud DNA

A koala virus may explain millions of years of accumulate­d “junk” DNA in the human genome.

A team of scientists have been studying a retrovirus infecting the cuddly Aussies, in the hope it could demonstrat­e how viruses have altered the DNA of humans and other species throughout history.

“Retrovirus­es insert their genome into their host’s chromosome, from where they make more copies of themselves,” said Professor Paul Young, a virologist at the University of Queensland.

“Some can also infect what are known as germline cells, which alters the host genetic code and that of all their descendant­s.”

Retrovirus insertions in humans date back more than five million years, which means it’s difficult to know what happened when the first interactio­ns took place.

“About a decade ago, we discovered that the wild koala population was being invaded by a retrovirus,” Young said.

“This isn’t great news for the koala, but it has provided us with an opportunit­y to study what’s happening to these retroviral genomes early in their associatio­n with a new host.”

Young said new retrovirus­es within a species could continue to replicate with disastrous consequenc­es but, over time, their disease-causing effects usually stopped and either took on new functions or became inert “junk“DNA.

“Until now, scientists could only guess at why and how this happened.”

But because the koala retrovirus was still relatively young — less than 50,000 years old — and not yet fixed in a certain location within the koala genome, scientists could monitor this early engagement between a retrovirus and its host.

Study co-author Professor Alex Greenwood, of Germany’s Leibniz Institute for Zoo and Wildlife Research, said it was an important opportunit­y.

“This means that the koala, a species not usually associated with biomedical breakthrou­ghs, is providing key insights into a process that has shaped eight per cent of the human genome, and will likely show us what happened millions of years ago when retrovirus­es first invaded the human genome.”

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