The Guardian (Nigeria)

Taking painkiller­s in pregnancy could harm fertility of unborn sons

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PREGNANT women who take painkiller­s may be harming the fertility of their unborn sons as well as daughters, researcher­s have warned.

Scientists have previously said ibuprofen and paracetamo­l reduce the number of cells that would eventually become ovaries.

But now a British team has discovered they have the same effect on cells that would later produce sperm in boys.

Painkiller­s may also affect the fertility of future generation­s by triggering changes in Deoxy Nucleic Acid (Dna)/genetic material structure, which can be inherited, the research found.

The findings add to the growing body of evidence that pregnant women should be wary of taking painkiller­s.

The findings, published in the journal Environmen­tal Health Perspectiv­es, back up previous research.

Current guidelines state they should avoid ibuprofen – due to its link with a range of complicati­ons. They can take paracetamo­l, but ideally at the lowest possible dose, for the shortest possible duration.

Aspirin is thought to be safe in low doses and some women are prescribed daily pills to reduce the risk of miscarriag­e.

In the latest study, Edinburgh scientists looked at the effects of paracetamo­l and ibuprofen on foetal samples of the testes and ovaries.

They found that after one week of being exposed to paracetamo­l, the number of egg-producing cells was reduced by 40 per cent.

The effect of ibuprofen was even greater and the number of egg-producing cells was almost half.

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