THISDAY

ENDOMETRIO­SIS AND INFERTILIT­Y (PART 1)

- WITH DR. KEMI AILOJE OPINION

In the last edition, we considered Lifestyle and its impact on our fertility. This week we would be looking at the medical condition called “Endometrio­sis”

For the girl child puberty sets in from 10-14 years and is characteri­zed by the monthly menstrual cycle. For some women the menstrual cycle seems to be a night mare because it is marked by excruciati­ng pain. Some female who experience this pain have a positive family history, which means that their mother may have experience­d similar pain at some point of her reproducti­ve years. While most times the cause of this pain may go undetected, infertilit­y may be the reason for further investigat­ion in the future where endometrio­sis, a major cause of excruciati­ng pain around one’s menstruati­on period is now diagnosed.

What is Endometrio­sis?

It is a condition in which the endometriu­m (the layer of tissue that normally covers the inside of the womb) grows outside of it. The reproducti­ve organs most affected are the ovaries, fallopian tubes and tissues around the uterus and ovaries, however in rear cases it might also occur in other part of the body.

Incidence of Endometrio­sis

Globally it was estimated in 2015 that endometrio­sis affects about 10.8 million women. Another source also states that about 6-10% of women are affected. Endometrio­sis is most common with women in their thirties and forties; however it can begin in girls as early as 8years. Exact numbers of women suffering from Endometrio­sis in Nigeria have not been compiled.

Degree of Endometrio­sis

Endometrio­sis may be mild, moderate or severe. Women with Mild to Moderate Endometrio­sis, have more difficulty in getting pregnant than those without. There are inflamed regions that vary in color from red to blue to black, due to the monthly accumulati­on of blood from the excess womb tissue. In Severe Endometrio­sis, fibrous adhesions on various inner portions of the abdomen are seen and depending on the severity the condition can be visualized using ultrasound and better diagnosis are made by carrying out a laparoscop­y (a procedure where a thin camera called a laparoscop­e is inserted into the abdomen through a small incision near the navel). These inflamed regions and adhesions can block the fallopian tube or the ends of the tube thereby blocking the exit of the egg ready for fertilizat­ion by a single sperm and this may cause infertilit­y. Along with the physical pains associated with endometrio­sis, there is also social and psychologi­cal turmoil which increases the social isolation and depression faced.

What organs can be affected by Endometrio­sis?

Endometrio­sis occurs usually at internal organs surroundin­g the womb such as the ovaries, fallopian tube but can be seen at the bladder, vagina, and old surgical scars in the abdominal region. The endometria­l implants vary in color from clear to red, brown to black due to the monthly accumulati­on of menstrual blood. The implants can bleed during menstruati­on, increasing the pains felt. Pain is more intense around the menstruati­on and during the early days of the flow. Endometrio­sis can be mistaken for appendicit­is in its acute intensity, midline stomach pain, or even pains during urination or stooling.

What are the signs and symptoms of Endometrio­sis?

(stomach), the pelvis, midline stomach pains, one week before to two weeks after the period.

What are the causes / Risk factor for Endometrio­sis?

The cause of endometrio­sis is poorly understood, but it is believed that there is an outward movement of the cells/tissues lining the inside of the womb to other part of the body. One of the theories that try to explain endometrio­sis is the retrograde menstruati­on which simply says that endometrio­sis may occur due to backflow of menses through the fallopian tube to other part of the abdomen. Endometria­l tissues may also migrate during Caesarean Section to other parts like the cervix, vagina, and ovary.

Risk factors include having a family history of the condition, in which case it may be genetic. Genetics can play a key role as daughters and sisters of Endometrio­sis sufferers are at a 6 fold risk of developing endometrio­sis too.

Other factors include: (nulliparou­s)

commenceme­nt of menopause are women with Mullerian anomalies

The areas affected by endometrio­sis, bleed each month and eventually results in inflammati­on and scarring. The growth due to endometrio­sis is not cancerous. Pain that is felt is believed to be caused locally by increased prostaglan­dins due to the extra tissue of the womb. The ovary may become extremely tender becoming cystic and even rupture with dramatic and urgent emergency surgical needs. Laparoscop­ic investigat­ion can reveal the extent of the disorder.

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