THISDAY

Evolution of Fertility Centres in Nigeria

- Dr. Toyin Ajayi •Dr. Ajayi is the medical director of Bridge Clinic.

In the industrial age, fertility rates began to decline worldwide. Between 1870 and 1920, fertility rates fell by 30 to 50 percent in Western Europe and the United States. Orthodox treatments were limited in scope and efficacy; and in many cases spiritual and other alternativ­e means were employed by desperate would-be parents with varying outcomes.

In 1978, Drs. Patrick Steptoe and Robert Edwards of Oldham General Hospital, in Odham, England, after over two decades of research, performed the world’s first successful IVF (In vitro fertilizat­ion) procedure which led to the birth of Baby Louise Brown, the world’s first ‘test tube’ baby on July 25, 1978 in Oldham, England. In vitro fertilizat­ion is a medical procedure in which an egg is removed from the woman’s ovaries and fertilized with sperm in a laboratory. The fertilized egg, now called an embryo, is returned to the woman’s womb to develop.

This revolution­ary feat led to a surge in the establishm­ent of fertility centers as well as the developmen­t of more sophistica­ted techniques such as IUI (inter uterine inseminati­on) and ICSI (Intracytop­lasmic Sperm Injection).

In the United States of America, the first IVF baby was born in 1981; in France, 1982; Italy 1984; and Germany,1982. The first successful IVF procedure in Africa was in 1984 in South Africa.

Stringent guidelines and regulation­s were quickly set up to control the proliferat­ion of sub- standard facilities in most of the developed world, but Africa has lagged behind. In Nigeria, at present, there are no regulation­s in place to specifical­ly control the activities of fertility clinics.

The first claim to a successful IVF birth in Nigeria was made by Professors Giwa Osagie and Ashiru at the Lagos University Teaching Hospital in 1986. Dr. Ibrahim Wada of Nisa Premier Hospital reported an IVF birth in 1999. Many unverifiab­le claims of successful IVF procedures have been made since then.

To meet the ever-increasing demand for fertility treatment, many fertility centers have been establishe­d in Nigeria. However, the relatively high cost associated with treatments as well as the general lack of awareness in the populace has forced many would-be parents to turn to spiritual and traditiona­l healers in their search for a child. The absence of a regulatory framework has encouraged the proliferat­ion of quacks who often do more harm than good.

Bridge Clinic was set up as the first focused fertility center in Nigeria in 1999 and reported the birth of the first ICSI babies in Nigeria in 2000. This remarkable achievemen­t was followed up by it’s becoming the first fertility clinic in Nigeria, nay West Africa to be awarded the coveted ISO 9001 Quality Management Certificat­ion in 2004 by TUV Austria.

As there were no accredited embryologi­sts in the country at the time, Bridge Clinic began operations with technical support from a team from King’s College, London, led by Dr. John Parsons who had been on the pioneering team that performed the world’s first successful IVF procedure in 1978. This support greatly facilitate­d the rapid transfer of technology to Nigeria.

Bridge Clinic’s focus on staff training and collaborat­ion with internatio­nal experts has had a positive multiplier effect on the fertility landscape as many of their alumni hold key positions in fertility clinics, both locally and in the diaspora. It plays a key role in advancing medical education and provides opportunit­ies for healthcare profession­als to receive specialize­d training in the field of reproducti­ve medicine, contributi­ng to the developmen­t of a skilled workforce in this critical area of healthcare.

In an interview with Dr Toyin Ajayi, The Medical Director of Bridge Clinic, she revealed that there were several obstacles that had to be overcome in fulfilment of their mission. Infrastruc­tural, financial and technical challenges had to be overcome. Accurate laboratory testing, essential to the operations of a fertility clinic, was also lacking in the country. This led to the formation of Pathcare Ltd, a laboratory and medical logistics firm, as a necessary adjunct to the operations of Bridge Clinic.

As demand for IVF continues to expand, there has been an uncontroll­ed proliferat­ion of fertility clinics to meet this need. Exploitati­on of desperate would-be parents is rife as unscrupulo­us and unethical operators take advantage of their distress. This phenomenon is not restricted to Nigeria but in more developed countries, stringent licensing systems control the deployment and assure the quality of the procedures carried out by fertility clinics.

In the United Kingdom for example, for a fertility center to begin operations, three regulatory licences are required: Human Fertilizat­ion and Embryology Authority (HFEA); Care Quality Commission (CQC); and the Home Office Controlled Drugs licence. Although these regulatory requiremen­ts are not yet in place in Nigeria, the Bridge Clinic operates according to these standards to ensure consistent and effective service delivery.

What’s the future? The fertility sector is expected to grow in Nigeria like in other parts of the world due to the global decline in fertility rate. The sector players in Nigeria need to acquire emerging cuttingedg­e technologi­es like the use of AI in embryo selection amongst others. According to Dr Toyin Ajayi, one of the values at Bridge Clinic is “Innovation.” The Clinic is always at the forefront in the adoption of new technologi­es that improve treatment outcomes.

On the part of the government, there is need to set up a legal and regulatory framework to oversee fertility centers. The Lagos State government is already in the forefront of this as some papers are in the works. But the need for an oversight at the federal level cannot be overemphas­ized. The barrier to entry needs to be raised to avoid the incursion of quacks. Fertility treatment is based on trust and ethics, and that must be upheld all the time.

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