The Pak Banker

The ill-advised push to vaccinate the young

- Martin Kulldorff

The idea that everyone must be vaccinated against COVID-19 is as misguided as the anti-vax idea that no one should. The former is more dangerous for public health. The COVID19 vaccines have been one of the few bright spots during this pandemic. While anyone can get infected, the old have a thousand-fold higher mortality risk than the young.

By vaccinatin­g older people, the country has saved thousands of lives.

There is intense pressure on young adults and children to be vaccinated. Universiti­es such as Colombia, Cornell, Harvard and Stanford require all students to get the shot as a condition of attending college normally.

Young people looking for work are discrimina­ted against if they are not vaccinated. It makes public health sense to require some vaccinatio­ns in some settings. However, in the case of COVID vaccines for young people, such mandates harm public health.

First, all medical interventi­ons should pass the test of providing more benefits than risks. For the COVID vaccine, this is decidedly true for older population­s but it is not yet clear for younger people. While we know that COVID vaccines have common but mild adverse reactions, we will not know enough about rare but serious adverse reactions until a few years after vaccine approval.

For older people, this does not cause a dilemma. Even if there is a small risk of a serious adverse reaction, that is still better than the much higher risk of dying from COVID. Hence, we should do everything we can to encourage vaccinatio­n for older people, including less affluent people whom our health care system often has difficulty reaching.

For younger adults and children, it is a different story, as their mortality risk is extremely low. Even a slight risk of a serious vaccine adverse reaction could tip the benefit-risk calculatio­n, making the vaccine more harmful than beneficial. We have already observed rare problems with blood clots (J&J vaccine) and myocarditi­s (inflammati­on of the heart muscle, Pfizer and Moderna) in younger people, and additional equally serious issues might still be found.

Under such uncertaint­y, vaccine mandates are unethical. University presidents or business leaders should not mandate a medical interventi­on that could have dire consequenc­es for the health of even a few of the people in their charge.

Second, recovered COVID patients have strong long-lasting protection against severe disease if reinfected, and evidence about protective immunity after natural infection is at least as good as from the vaccines. Hence, it makes no sense to require vaccines for recovered patients. For them, it simply adds a risk, however small, without any benefit.

During the pandemic, the profession­al laptop class protected themselves by working from home while exposing the working class that brought them food and other goods. It is now the height of hypocrisy to recognize immunity from vaccinatio­ns but not immunity from those exposed while serving the laptop class.

Third, the pandemic is global.

In most countries, older high-risk people have not yet been vaccinated. With a global vaccine shortage, every dose given to a low-risk young adult in the United States means one fewer dose available for high-risk older people in Brazil, Congo, India or Mexico.

When American universiti­es and companies mandate vaccinatio­ns, they are not only failing the young in this country, they are also indirectly responsibl­e for the death of older people in the developing world.

Fourth, public health relies on trust to be effective. But the public will not trust public health advice unless public health officials reciprocat­e by trusting in the public.

Vaccine mandates go against this basic principle of public health. They will backfire by increasing vaccine hesitancy, not just for the COVID vaccine but also for other essential vaccines, including polio, measles, human papillomav­irus and meningitis, to name a few. We have spent decades building trust in vaccines by informing people about their benefits and risks.

 ??  ?? ‘‘When American universiti­es and companies mandate vaccinatio­ns, they are not only failing the young in this country, they are also indirectly responsibl­e for the death of older people in the
developing world.”
‘‘When American universiti­es and companies mandate vaccinatio­ns, they are not only failing the young in this country, they are also indirectly responsibl­e for the death of older people in the developing world.”

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