Stem cells hold promise to treat Alzheimer’s

A TEAM of Japanese researchers has found a new drug combina role in causing Alzheimer’s dis

The scientists believe their findings, published in the online edition of the Cell Reports - drug to treat Alzheimer’s — a progressive disease character - fects tens of millions of people worldwide. There is so far no - ment for Alzheimer’s.

created so- called induced pluripotent stem cells ( iPS cells) from individuals, including patients with Alzheimer’s, and then cultivated them in vitro to replicate diseased brain tissue.

The researchers created cortical neurons derived from iPS cells from five patients with - tients with sporadic Alzheimer’s, which means there is no

most effective combination to re existing drugs — bromocriptine, -

The team said in its report that and potent” effect and “promises to be useful” for the development of drugs to treat Alzheimer’s.

Haruhisa Inoue, a professor with the Center for iPS Cell Re team, expressed hope that the combination would prove more effective than existing options.

“I hope to tap into the merits of [using] existing drugs that have a period of time,” Inoue said in an email to The Japan Times.

showed that the accumulation of factor in Alzheimer’s.

“There was an effect at the cellu the effect on humans,” Inoue said.

First time to use combinations

in the world a combination of existing drugs has been shown beta protein.

Other researchers have also tried beta the protein. But their efforts have failed during the clinical trial stage due to the side effects of drug candidates, prompting researchers

Able to be reprogrammed to grow in human tissues and organs, iPS cells are recognized as a promising tool for drug development and regenerative medicine.

Alzheimer’s is the most com - cell damage.

According to Alzheimer’s Disease International, the number of people with dementia was estimated at 46.8 million glob