The Manila Times

Cheap malaria vaccine to start Africa rollout

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The world’s biggest vaccine maker will start rolling out a cheap new malaria inoculatio­n in Africa from May, bolstering the fight against one of the deadliest infectious diseases globally.

The mosquito-borne malady kills more than 600,000 people a year, 95 percent of them in Africa, according to the World Health Organizati­on (WHO).

It is more fatal among the young, and the annual toll of malaria deaths includes nearly half a million African children under five years old.

The Serum Institute of India (SII) this year plans to ship 25 million doses of the new vaccine, developed along with Oxford University researcher­s and known as R21.

“In terms of importance and saving lives ... it’s going to be a hugely impactful vaccine,” SII chief executive Adar Poonawalla told AFP.

“We’ve offered these vaccines to the African continent at $4 or less in the first year itself. And then as we scale up, maybe we can bring that down a little bit further.”

The R21 vaccine, a three-dose course and booster shot for children between 5 and 36 months, is the second malaria shot approved by the WHO.

Yet, researcher­s say it will be cheaper than the other vaccine produced by British pharma giant GlaxoSmith­Kline.

The WHO said its rollout was expected to greatly expand supply to meet high demand from African countries.

The SII has been the largest vaccine manufactur­er globally for several years but saw its profile rise substantia­lly after manufactur­ing millions of cheap Covid vaccine shots for export at the height of the pandemic.

With demand for coronaviru­s prevention waning, it has repurposed some pandemic-era facilities to combat other diseases at its sprawling factory complex in Pune, a few hours’ drive from business capital Mumbai.

Small glass vials are pumped with R21 doses and whizzed off on a conveyor belt for quality checks and packaging ahead of their looming export.

Poonawalla says the institute’s goal is to roll out R21 in a few countries before the main malaria season starts in about six to seven months.

“Ideally, we should have vaccinated the people most vulnerable at risk. That’s the target,” he said, adding that production would eventually reach 100 million R21 doses per year.

SII research and developmen­t director Umesh Shaligram said the vaccines would be shipped towards the end of April with deployment to start by May and June.

The vaccines will mostly be bought and distribute­d through the United Nations Children’s Fund (Unicef) and Gavi, a global vaccine alliance.

Chad, Central African Republic, DR Congo, Mozambique and South Sudan will be the first five countries to receive R21 doses, a Unicef spokesman told AFP.

“Uganda and Nigeria are planning to introduce it later in the year,” the spokesman added.

 ?? AFP PHOTO ?? VACCINE ROLLOUT
In this photograph taken on Feb. 27, 2024, a staff works inside the human papillomav­irus vaccine manufactur­ing unit of the Serum Institute of India in Hadapsar, Pune.
AFP PHOTO VACCINE ROLLOUT In this photograph taken on Feb. 27, 2024, a staff works inside the human papillomav­irus vaccine manufactur­ing unit of the Serum Institute of India in Hadapsar, Pune.

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