Philippine Daily Inquirer

NEW SWINE FLU VIRUS INFECTS FARMWORKER­S, POSES FRESH PANDEMIC THREAT

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WASHINGTON—RESEARCHER­S in China have discovered a new type of swine flu that has infected a small number of swine industry workers and is capable of triggering another pandemic, a study published on Monday in the US science journal PNAS said.

According to blood tests which showed up antibodies created by exposure to the virus, 10.4 percent of swine workers had already been infected by the new zoonotic pathogen called G4 virus.

The tests showed that as many as 4.4 percent of the general population also appeared to have been exposed.

The virus has therefore already passed from animals to humans but there is no evidence yet that it can be passed from human to human—the scientists’ main worry.

“It is of concern that human infection of G4 virus will further human adaptation and increase the risk of a human pandemic,” the researcher­s wrote.

Researcher­s said G4 was geneticall­y descended from the

H1N1 strain that caused a pandemic in 2009.

It possesses “all the essential hallmarks of being highly adapted to infect humans,” say the authors, scientists at Chinese universiti­es and China’s Center for Disease Control and Prevention.

179 flu viruses

From 2011 to 2018, researcher­s took 30,000 nasal swabs from pigs in slaughterh­ouses in 10 Chinese provinces and in a veterinary hospital, allowing them to isolate 179 swine flu viruses.

The majority were of a new kind which has been dominant among pigs since 2016.

The researcher­s then carried out various experiment­s including on ferrets, which are widely used in flu studies because they experience similar symptoms to humans—principall­y fever, coughing and sneezing.

G4 was observed to be highly infectious, replicatin­g in human cells and causing more serious symptoms in ferrets than other viruses.

Tests also showed that any immunity humans gain from exposure to seasonal flu does not provide protection from G4.

Asked about the virus on Tuesday, Chinese foreign ministry spokespers­on Zhao Lijian told a regular press briefing that China “has been paying close attention to its developmen­t” and will take all needed action to prevent its spread and any outbreaks.

The study’s authors called for urgent measures to monitor people working with pigs.

“The work comes as a salutary reminder that we are constantly at risk of new emergence of zoonotic pathogens and that farmed animals, with which humans have greater contact than with wildlife, may act as the source for important pandemic viruses,” said James Wood, head of the department of veterinary medicine at Cambridge University.

A zoonotic infection is caused by a pathogen that has jumped from a nonhuman animal into a human.

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