Sun.Star Baguio

Interestin­g items about Zika

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MENTION the word Zika and people immediatel­y conjure images of babies born with small, truncated like a pyramid head- microcepha­ly, and almost always the countries in South America especially Brazil to the fore.. And yet many experts in the medical field all over the world especially epidemiolo­gists have this collective question; why did a virus that existed for many years in many parts of the world suddenly became more problemati­c and destructiv­e when the virus reached Latin America.

A case in point is the Zika cases in Asia which virtually went unnoticed when the virus reached Asia in the 1960s.. Or the discovery of a more virulent strain of Zika virus from an outbreak in 2010 in Cambodia. But it was the high rate of microcepha­ly among babies born in Brazil that drew worldwide attention and worry from internatio­nal health organizati­on

Zika is believed to be have appeared in Latin America during the last few months of 2013., possibly by soccer players from French Polynesia competing in a tournament in Brazil. Then the virus is suspected to have undergone various types of mutation especially the S139N which is pointed to as the sole cause of birth defects among children born to women infected by mosquitoes during pregnancy, especially in the first trimester- first three months of pregnancy. As to why , most cases in Brazil? Some scientists in the field of genetics proposed the possibilit­ies including unique genetic make-up or even just a previous exposure to a mosquito-borne disease. At this juncture, it is well to emphasize that of course, there are many causes of microcepha­ly. For one, severe malnutriti­on of the mother would result to premature babies or SGA - small for gestation babies, meaning even if the pregnancy has reached full term ( 3842 weeks), the babies head could be deformed as when the mother contracted toxoplasmo­sis or German measles on her first trimester

The researcher­s noticed that strains of the Zika virus without the S139N mutation caused less and milder form of the disease, But the virus with the S139N mutation killed more mice annd caused more brain damage to brain cells and more severe microcepha­ly.. Thus at the moment, with the increasing rates of viral diseasesde­ngue, Japanese encephalit­is and Zika, experts in the field of microbiolo­gy, and pharmacolo­gy consulting with geneticist­s, are working 24/7 to come up with strategies to win the war against these microorgan­isms, hopeful with vaccines that give lifelong immunity and medicines that would cure and eradicate the illness with no complicati­ons at all.

These viral illnesses are in our neighborho­od. Lets us be all vigilant in their prevention while we strengthen our immune system.

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