Sun.Star Baguio

How’s your immunity?

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IMMUNITY is the scientific study of the immune system and the different immune responses as well as defense mechanisms against disease-causing agents, with experts in this specialty called immunologi­sts. According to currently accepted doctrine, the primary functions of the immune system are to differenti­ate between self- bodily items that are within the body of the person- and non self or anything foreign, with the inherent ability and strength to destroy that which is non-self.

Humoral immunity always involves the production of antibodies in response to antigens which are molecules that are considered foreign or non self when introduced into the body, thus are capable of stimulatin­g the production of antibodies, which are proteins which are capable of neutralizi­ng and fighting the specific antigen, in other words, there is a very high level of specificit­y in terms of antigen-antibody interactio­n, thus antibody X responds only to antigen A, while antibody Y reacts only to antigen B. In short, humoral immunity is also called antibody-mediated immunity.

Cell-mediated immunity includes many cell types found inside the body, mostly in the blood like macrophage­s- big cells capable of eating the enemy-, different types of T lymphocyte­s like killer cells, cytotoxic cells- , and granulocyt­es which include neutrophil­s, eosinophil­s and basophils.

Acquired immunity that results from the active production or receipt of protective antibodies during one’s lifetime is called acquired im- munity. The antibodies we produce after getting sick is called natural active acquire immunity; natural because getting sick is a common experience of every human being, active because it is our own body that produces the antibody whereas vaccinatio­n results to artificial active acquired immunity. Vaccines are made of weakened or attenuated portions or parts of microorgan­isms which when ingested or injected into a person, would be considered as foreign or non self, thus the immune system mounts an aggressive strong response against the microbe, but not strong enough to cause a full-blown disease caused by the microbe from where the vaccine was sourced .

Immunity passed on from one person –pregnant woman- to her growing fetus is a form of artificial passive acquired immunity. While the growing fetus is still inside the womb of the mother, antibodies from the mother pass thru the placenta, umbilical cord blood vessels to the fe-

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