Sun.Star Cebu

Gassing or freezing?

- ZOSIMO T. LITERATUS zim_breakthrou­ghs@yahoo.com

Globally, cervical cancer continues to top the disease burden of countries with low- to middle-income levels. According to Miriam Cremer and eight other colleagues at Basic Health Internatio­nal (BHI) in New York, the persistent public health challenge remained so evidently due to the gap between screening outcomes and the availabili­ty of effective but affordable treatment, particular­ly in remote areas around the world.

The team published their report in this year’s issue of the Global Health: Science and Practice.

Today, the most innovative, relatively inexpensiv­e therapeuti­c approach against cervical cancer with impressive outcomes is “cryotherap­y” (literally, “treatment by extreme cold”), which is also being referred to as “cryosurger­y” (literally, “operation by extreme cold”). It works by exposing a tumor in freezing temperatur­e of up to -105 degrees Celsius, killing the cancerous cells within before removing the tumor.

Unfortunat­ely, this treatment method is not yet available in the Philippine­s, although past news reports referred to a Chinese hospital in Guangzhou that specialize­d in this approach. Neverthele­ss, it is to our advantage to know about this technology.

The standard form of cryotherap­y is gas-based, which uses either compressed carbon dioxide or nitrous oxide gas. However, there are three challenges to this form.

First, procuring the gas can be difficult, especially in our country where the generation technology is either underdevel­oped or inexistent. Second, gas tanks may be accessible only in urban areas and not in remote locations. Third, high volume demand requires a large storage area because a standard size tank can serve only three patients. A non-gas option, which uses electricit­y, is still under developmen­t in the United States.

In the Cremer study, its advantages are clear over nitrous oxide-based machines. It has slightly deeper lateral freeze (i.e. in areas surroundin­g the point of applicatio­n - 7.93 mm) and wider freeze diameter (30.71 mm). Thus, it can treat larger tumors, which can generate a frozen tumor of 8.27 g. Its freeze depth is, however, smaller at 6.33 mm.

Moreover, it must be noted that unlike surgery, surroundin­g health tissues, blood vessels and nerves may be frozen as well when it is located within the effective freeze diameter. Here is what Brent Weeks wrote in The Broken Eye (2014): “More choices in a limited time didn’t mean you could do everything—it meant that you could do anything, so you probably did nothing, frozen with indecision.”

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