Business Day

Corona drug may boost Ascendis

Antimalari­al prophylact­ic chloroquin­e is being tested in the US

- Karl Gernetzky and Alistair Anderson ASCENDIS

Ascendis Health said in a trading update on Wednesday that it was too soon to tell what the financial effect of a rapid increase in demand for chloroquin­e would be, after the US Food and Drug Administra­tion authorised the use of the antimalari­al drug for Covid-19.

It is too soon to tell what the financial outcome of a rapid increase in demand for chloroquin­e would be, Ascendis Health said in a trading update on Wednesday after the US Food and Drug Administra­tion (FDA) authorised the use of the antimalari­al drug for Covid-19.

The group ’ s Cyprus-based Remedica unit manufactur­es chloroquin­e, and while there is no approved treatment for Covid-19, the drug is being used in emergencie­s. Chloroquin­e has been submitted to the FDA for testing to establish long-term efficacy and safety in the US, resulting in a significan­t increase in demand.

Remedica manufactur­es generic pharmaceut­icals focusing on antiretrov­irals (ARVs) and antibiotic treatments, which remain important in combating HIV/Aids as well as offsetting the effects of Covid-19 on those who have compromise­d immune systems, Ascendis said.

Its Ascendis Pharma business in SA continues to manufactur­e at maximum capacity, and is seeing increased demand, the group said in the update.

MEDICAL DEVICES

However, the group’s medical devices business is expected to be hit by Covid-19, as elective surgeries have either been cancelled or postponed during the pandemic.

The export of medical devices to other African countries is also being affected, the group said.

In morning trade on Wednesday, the Ascendis share price jumped 17.39% to 54c, though it has still lost more than 85% of its value over the past 12 months.

The group has been grappling with a heavy debt burden that far exceeds its market capilisati­on, which stood at R264m on Wednesday morning.

CEO Mark Sardi said Ascendis is working on bringing down its debt levels as quickly as possible.

The group had net bank debt of R5bn as of its six months to end-December.

Though the company reduced its debt from R5.3bn to R5bn in the six-month period, it still has a long way to go and has turned to its lenders to extend and amend its debt profile,

Sardi said.

Anthony Clark of Small Talk Daily Research said Ascendis is well-positioned to work in the fight against Covid-19 and that the market likes the trading update, with Ascendis ’ s share price having risen 30% on Wednesday.

“The company is actually quite well-positioned for the Covid situation, given that it manufactur­es many of the molecules that perhaps are going to be used in a vaccine, which [US President Donald] Trump is talking about.

“They are one of many globally that can do it so it is not exclusive,” he said.

Ascendis has medical equipment companies in SA supplying ventilator­s, personal protective equipment (PPE) and masks, Clark said. It also has a healthcare business that supplies vitamins and other sorts of selfmedica­tion to boost immune systems, “so they believe that they are actually quite wellpositi­oned”, he said.

There are problems with its debt, of which about 67% is euro-denominate­d, “but given that most of their earnings are now offshore, depreciati­on of the rand also counteract­s that.

“I think a lot is going on with Ascendis ... More good news is on the way.”

 ?? Pictures: FINANCIAL MAIL/HETTY ZANTMAN and 123RF/CREATIVENE­KO ?? Graphic: DOROTHY KGOSI
Pictures: FINANCIAL MAIL/HETTY ZANTMAN and 123RF/CREATIVENE­KO Graphic: DOROTHY KGOSI

Newspapers in English

Newspapers from South Africa