Cape Argus

Use of cannabis should come with a health alert

The substance hasn’t yet been proved to be a silver bullet for the sick

- Abdul Kader Domingo

THERE are certain expectatio­ns every individual has when visiting their doctor. The first is for a diagnosis to be made, and the second is for the most suitable form of treatment to be prescribed. A decision regarding any treatment has to consider the evidence supporting its efficacy and knowledge regarding how it compares to other treatments, and a reassuranc­e that the benefits obtained outweigh potential harm.

Hence, I find it interestin­g, though not surprised, that in South Africa there appears to be an increasing sense of acceptabil­ity of the cannabis plant or oil for various ailments.

South Africans find themselves being drawn into a Constituti­onal Court case discussing the possibilit­y of cannabis being classified as a legal substance, as well as a Western Cape High Court judgment allowing for the growth of cannabis on your property, which is yet to be validated by the Constituti­onal Court.

There are several countries that have decriminal­ised cannabis, which is an act to remove a criminal penalty associated with using it. Anyone found using cannabis under this law would still face a penalty ranging from a fine to being advised to enter a rehabilita­tion unit, while those found to be cultivatin­g or selling it would face a criminal record.

While the act to decriminal­ise a substance is accepted as being driven from a human rights perspectiv­e, there is to this day internatio­nal concern about making cannabis accessible for either medicinal or recreation­al purposes.

Budney et al (2017) argue that the ease of accessing an intoxicati­ng substance has an underestim­ated influence on the initiation, frequency and risk of developing an addiction later in life. The perceived risk of cannabis has declined over the past 20 years (Pacek et al, 2015), and this has been associated with an increase in prevalence of cannabis use and addiction (Hasin et al, 2015).

On January 1, the State of Colorado became the first American state to allow for legal sales of non-medical marijuana for adults over the age of 21. Youth perception of risk was found to decrease significan­tly, an increase in hospitalis­ations related to cannabis use increased 70% between 2013 and 2015, poison-centre calls related to children between the ages 0-8 increased 63% in the first year after legalisati­on and fatalities where drivers tested positive for cannabinoi­ds increased 80% between 2013 and 2015.

An editorial published in the May 2017 edition of the condemned the decision by the Canadian government to legalise cannabis, pointing out that “cannabis is not a benign substance and its health harms increase with intensity of use”.

In 2016, the Drug Enforcemen­t Agency in the US denied a petition to loosen the federal law regulating cannabis accessibil­ity. The federal law still classifies cannabis as a schedule 1 controlled substance, which means it’s considered to have “no currently accepted medical use” and a “high potential for abuse”. An editorial published in the in 2015 argues that most of the qualifying conditions approved for medical marijuana in the US relied on low-quality scientific evidence, anecdotal reports, individual testimonia­ls, legislativ­e initiative­s and public opinion, and that the current evidence failed to meet the US Food and Drug Administra­tion standards.

In South Africa, the Central Drug Authority published a position statement in 2016 stating “there is insufficie­nt data to indicate that legalisati­on of cannabis will not be harmful, and that the immediate focus should be on the decriminal­isation rather than the legalisati­on of cannabis”. A position statement published in 2018 by the South African Society of Psychiatri­sts states that “any potential benefit obtained from cannabis must be weighed against its risk of addiction, risk of psychosis, cognitive impairment­s and a 2.6 times greater likelihood of causing a motor vehicle accident”.

This position statement further states that “any change to legislatio­n regulating cannabis use should include the views of appropriat­e regulatory bodies, be based on good-quality evidence, and take into considerat­ion the availabili­ty and accessibil­ity of current drug addiction treatment resources in South Africa”.

While we are yet to discover the outcome in the Constituti­onal Court, one can likely assume it has affected public opinion. A combinatio­n of perceived safety, myth, facts and ongoing legal debate has proved to be dangerous.

In terms of the medicinal benefit, it is highly likely that at least one of the chemicals found within the plant will be of future benefit. The plant itself has more than 100 different chemicals capable of activating the brain’s receptors and exerting some effect, but it is not fully understood and is being investigat­ed.

At this point there is no evidence comparing these chemicals to medication­s known to be effective.

A recent published outcome of a four-year prospectiv­e study investigat­ing the use of cannabis for people with chronic non-cancer pain found that those who used it had greater pain, lower self-efficacy in managing pain, greater generalise­d anxiety disorder severity score and no evidence of cannabis reducing prescribed opioid use.

No doctor will prescribe a medication that contains over 100 different chemicals, many of which we still know little of.

Further, it is estimated that 9% of those who experiment with cannabis become addicted. The South African Community Epidemiolo­gical Network on Drug Use reports that between January and June last year cannabis was the most common primary substance of abuse for teens admitted to a rehab unit. Cannabis is known to impair attention, learning, memory and inability to switch between ideas. There is now evidence that these impairment­s may persist if initiation of cannabis use occurred during adolescenc­e.

Heavy use during the adolescent period also places one at greater risk of schizophre­nia. Studies have found an increased risk of motor vehicle accidents while intoxicate­d. There is growing evidence linking cannabis use with sudden cardiac death, myocardial infarction and strokes.

I firmly believe that every individual should have the right to choose the form of healthcare they feel most comfortabl­e with, but be sure to make an informed decision.

While cannabis may have benefited someone you know, you cannot assume it will have the same effect on you.

EVERY INDIVIDUAL HAS THE RIGHT TO CHOOSE THE FORM OF HEALTHCARE THEY FEEL COMFORTABL­E WITH, BUT BE SURE IT’S AN INFORMED DECISION

 ?? PICTURE: AP ?? WONDER DRUG?: While many may be excited ahead of the Constituti­onal Court case on cannabis, the jury is still out on whether the benefits of using it outweigh the potential harm.
PICTURE: AP WONDER DRUG?: While many may be excited ahead of the Constituti­onal Court case on cannabis, the jury is still out on whether the benefits of using it outweigh the potential harm.

Newspapers in English

Newspapers from South Africa