Mail & Guardian

Molecular genetic services to agricultur­al industries

Research leading to innovation by a team or individual through an SMME

- Shelli Nurcombe-Thorne

CenGen, a privatelyo­wned company that provides molecular genetic services to agricultur­al industries, is proof that dynamite comes in small packages. What began as a one-woman business has grown to a team of six focused and highly productive members, whose outputs are comparable with those of far larger research groups worldwide.

CenGen is recognised by internatio­nal role players as an excellent research partner and thus secures significan­t global funding for its groundbrea­king work in the field of molecular genetics.

According to CenGen founder and director, Dr Renée Prins, the company’s flagship research project is an attempt to clone the first wheat disease-resistant gene in South Africa. CenGen collaborat­es closely with colleagues at Zürich University and the University of the Free State to isolate the gene sequence of this diseaseres­istant gene — something that could prove to be an agricultur­al game-changer.

Prins grew up on a farm and first discovered genetics in biology class. She registered for a BSc Agric and postgradua­te studies in genetics at Stellenbos­ch University. It was during these years that she became fully immersed in researchin­g the genetics of wheat. “It opened up a completely new world to me,” says Prins. “I really liked the concept of taking on the responsibi­lity of finding answers to a specific research questions.”

According to Prins, molecular genetic research and its effective implementa­tion in South African crop breeding programmes were virtually non-existent 15 years ago. This, coupled with an evident skills shortage in science and lack of scientific job opportunit­ies in rural areas, seeded the launch of CenGen in 2003.

“Our core focus is the implementa­tion of molecular genomics technologi­es in a variety of plants, as well as various other research projects,” says Prins. “On the research front, we collaborat­e with leading scientists to address and solve problems in major crops such as wheat, barley and grape cultivars. In terms of applicatio­n, we have been involved in a number of projects, including the implementa­tion of DNA technologi­es in wheat breeding cycles and DNA ‘fingerprin­ting’ to determine cultivar identity in juvenile fruit trees and grapevines.”

Prins explains that gene mapping has the power to completely transform crop breeding programmes. CenGen’s input on rust resistance in wheat and fungal resistance in barley and grapes, among others, continues to assist crop breeders as and when new findings are made.

“I find it very rewarding when I drive past a crop growing on a farm and know that we have ascertaine­d its ‘inside’,” she says. “It is so rewarding to know that we have done something, albeit small, that has contribute­d to how it is produced and the fact that it will actually be used to feed people.”

Going forward, Prins sees CenGen continuing to expand the company’s expertise from traditiona­l grain crops to many other species over time, and to offer the same standard of knowledge and services to a growing number of agri-industries.

“However,” she concludes, “every success at CenGen is not an individual’s achievemen­t but the collective result of a fantastic, focused, productive and exceptiona­lly passionate team.”

 ??  ?? CenGen founder and director Dr Renée Prins.
CenGen founder and director Dr Renée Prins.

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