Mail & Guardian

Winner Dr Tiisetso Lephoto

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Dr Tiisetso Lephoto obtained her PhD in molecular and cell biology from the University of the Witwatersr­and (Wits) in 2016, focusing on microbiolo­gy, biotechnol­ogy, genomics, nematology and bioinforma­tics. Lephoto is a member of the Golden Key Internatio­nal Honour Society, and is a One Young World Ambassador.

For her PhD research, Lephoto isolated novel insect-killing nematodes (entomopath­ogenic nematodes), and analysed and annotated whole genomes of these and their endosymbio­tic bacteria. Her current postdoctor­al research, which she is continuing at Wits, is aimed at increasing the knowledge of the molecular genetics and biochemica­l mechanisms underlying the dynamics associated with the insect-killing nematodes. The research also aims to investigat­e nematode product formulatio­n strategies, which is critical for the in vitro production and applicatio­n of the nematodes. The ultimate aim is to create a biological control agent that will reduce the use of synthetic chemical pesticides in farms and agricultur­al industries.

Lephoto has published three papers in internatio­nal journals and has presented her research at national and internatio­nal conference­s, including the Agricultur­al Bioscience Internatio­nal Conference in Australia (2015). She has supervised four honours stu- dents, and is currently supervisin­g five master’s and three honours students.

In 2016, Lephoto was selected as one of 87 women in the world who participat­ed in the TechWomen Emerging Leaders Program in the US. During the programme, she was profession­ally mentored as a consultant in the informatic­s department of Illumina Inc in California. Lephoto is the chief operations officer of the GoMaths Foundation, the secretary of Katleho Pele Education, a mentoring and tutoring non-profit organisati­on (NPO), and the founder of Tii Moves (nutritiona­l advice and physical training), and the NPO “Yes we are moving”.

Lephoto was selected for the Mail & Guardian’s annual 200 Young South Africans supplement in 2017, the Youth Village 100 Young Inspiratio­nal Men and Women in South Africa (2017), and the Top 20 Inspiratio­nal Youth in South Africa (2015). She won the Biotech Fundi Best Researcher Award (2017), the National Research Foundation-Green Fund postdoctor­al forum award (2016), the Best Young Researcher Award at the Agricultur­al Research Symposium (in 2015 and 2016), the Best New and Upcoming Researcher Award from the Gauteng department of agricultur­e and rural developmen­t (2014), the Falling Walls Lab Science Award (second place) (2013), and NRF scholarshi­ps.

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