Saturday Star

Tumours also an ailment of the past

Lump found on jaw bone of Homo naledi specimen suggests cancer is not necessaril­y a modern illness

- SHAUN SMILLIE

ALUMP found on an ancient j aw bone suggests t hat t umours and humans have had a long relationsh­ip that stretches back way before the ills of modern living.

Scientists beli eve t hey have found evidence of a small benign tumour on the right lower jaw of a Homo naledi specimen.

This announceme­nt comes as the Almost Human exhibition opened at Maropeng, billed as the largest public display of ancient fossil hominins, this week.

On display are Homo naledi skeletons from the Dinaledi and the newly discovered Lesedi chamber in the Rising Star cave system.

Edward Odes of Wits University, the lead researcher in the study, says it’s not known what the ef fect this non-life t hreatening t umour would have had on the adult naledi.

“It could have swelled up and caused a bit of discomfort,” he says.

He and his fellow researcher­s found the tumour using Micro CT scans and have publi s hed t hei r f i ndi ngs i n t he l atest copy of t he I nter nati onal Jour nal of Paleopatho­logy

T he p r e s e nc e of t he tumour may have made it dif ficult to chew. This is not the first tumour or cancer to have been discovered in the human fossil record.

Odes found evidence of osteosarco­ma, an aggressive for m of bone cancer, on a 1.7 million-year-old foot bone.

The foot bone was found at Swartkrans in the Cradle of Humankind. It’s not known if the cancer killed the individual.

Evidence for t he earliest known bony tumour in human prehistory was found not far from the Swartkrans site at Malapa also in the Cradle of Humankind.

This tumour was discovered on the 1.98 million-yearold vertebra of an Australopi­thecus sediba child.

The tumour, believes Odes, probably made it dif ficult for the sediba to climb.

The l atest t umour discovery is l ikely to help in our understand­ing of both tumours and cancers.

“What this means is that cancers and tumours are not a recent phenomenon,” says Dr Patrick Randolph- Quinney, of the University of Cen- tral Lancashire in the UK.

“We tend to think of cancer in particular as being a recent condition. An estimated eight million people around the world die from cancer each year, making the disease one of the most common causes of death in moder n humans, yet the origins of cancer have remained a mystery for many years.”

Randolph-Quinney added that many arguments around t he causes of t he disease blame moder n lifestyles and environmen­ts.

“While it’s true that the number of people af f ected by dif ferent types of cancer has risen since the industrial revolution, g roundbreak­ing research in 2016 found that the origins of cancer in the human family go back much further than we anticipate­d, in fact to almost two million years as we discovered last year with fossils from Swartkrans and Malapa caves,” Randolph-Quinney adds.

It was just over two weeks ago that scientists announced the date for the Homo naledi skeletons that were discovered in the Dinaledi chamber.

Through using various dating techniques, an internatio­nal team of scientists were able to date the skeletons to between 236 000 and 335 000 years.

But what still baffles scientists is how the naledi individual­s ended up in the cave system.

It’s been suggested that Homo naledi was placing its dead in the cave.

Odes says that there is no signs of trauma on the skeletons, and believes this would be unusual if this was some type of prehistori­c cemetery.

“The r e ma i n s we r e remarkably healthy; the question is what killed them off ?”

Those well-preserved mysterious remains in the Rising Cave system could one day provide more insight into the long relationsh­ip we have had with cancer.

Some of t hese cancers, explains Odes, are caused by viruses, and traces of their existence might still lie with those skeletons.

“I nevitably, DNA i s t he next f rontier t hat we are going to have to shoot for. That will identify viral signatures and disease markers,” says Odes.

 ??  ?? Paleoanthr­opologist Professor Lee Berger talks to media and guests as he walks through the opening of the new exhibition called ‘Almost Human’ at Maropeng, the official visitor centre of the Cradle of Humankind World Heritage Site.
Paleoanthr­opologist Professor Lee Berger talks to media and guests as he walks through the opening of the new exhibition called ‘Almost Human’ at Maropeng, the official visitor centre of the Cradle of Humankind World Heritage Site.
 ??  ?? The official opening of the new exhibition called ‘Almost Human’ at Maropeng, the official visitor centre of the Cradle of Humankind World Heritage Site.
The official opening of the new exhibition called ‘Almost Human’ at Maropeng, the official visitor centre of the Cradle of Humankind World Heritage Site.
 ??  ?? Steven Tucker, who discovered Homo naledi (skull, on right) at the official opening of the ‘Almost Human’ exhibition. The Sebida skull is on the left.
Steven Tucker, who discovered Homo naledi (skull, on right) at the official opening of the ‘Almost Human’ exhibition. The Sebida skull is on the left.

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