The Citizen (Gauteng)

Malaria cure takes leap

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Chisom Jenniffer Okoye

The Council for Scientific and Industrial Research is testing a new one-dose malaria capsule to replace the 24 capsules presently required to treat the disease and much cheaper.

Longi Kalombo, a chemical engineer researcher from the National Centre for Nano-structured Materials, said his team’s new technology using supercriti­cal fluid-based encapsulat­ion bioactives would also eradicate side-effects.

“We are trying to reduce the dose frequency of the current medication.

“For malaria, people are taking almost 24 tablets over three days.

“The aim of the team is to reduce the 24 tablets to one capsule.

“The simplest way to do it is to make an emulsion, produce a powder with that emulsion and put it in capsules.

“Then we can go from using so many tablets to just one dosage for malaria treatment.”

Kalombo also said that the onedose treatment would also improve compliance.

“The reason we are reducing the number of tablets is, firstly, because of compliance.

“We need to increase the compliance because if you don’t, you end up with resistance.

“If you have resistance, it means the current medication is not going to work and you then end up in a situation where people will be dying every single day.

“We hope that when we reduce the number of tablets and frequency of taking them, we will be increasing the compliance of the drug, which will then allow for the more effective treatment and cure of malaria.”

“Secondly, there are socioecono­mic benefits.

“When you are sick and you don’t go to work, the economy of the country is suffering and your family is also suffering.

“But if you can accelerate the process of healing, it means that you may only have to take one day off work.

“Also, having only a single dosage is cheaper, which means it will also be financiall­y beneficial for the families.”

The drug was currently still undergoing trials, but the team believed the product would come on the market soon.

People are currently taking almost 24 tablets over three days. The aim is to reduce that to one capsule. Also, having only a single dosage is cheaper, which is financiall­y beneficial for the families.

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