The Herald (South Africa)

SA first to roll out new drug to treat resistant TB

- Tanya Farber

SOUTH Africa’s Department of Health became the first in the world to announce the rolling out of a new and more tolerable drug to fight multidrug-resistant tuberculos­is (MDR-TB).

It was announced that the new drug‚ bedaquilin­e‚ would replace current treatment regimens for adolescent­s and adults from the start of their treatment.

Dr Norbert Njeka‚ a director in the department‚ confirmed the mass scale-up.

Njeka said those provinces not yet equipped for the rollout would be capacitate­d to do so.

South Africa being the first country to take this decision arose from the fact that it had been the first country to see the mass benefits of the new drug, which until now had been rolled out in small pockets across the country.

But the scale-up was likely to reduce the burden of the disease exponentia­lly, he said.

Each year‚ about half-a-million people contract MDR-TB across the globe‚ and South Africa carries a high burden with 19 000 of those.

Doctors Without Borders said in a statement it applauded the South African health department for being the “first country in the world to take this bold step aimed at scaling up access to an effective new drug‚ making MDR-TB treatment more tolerable‚ and reducing the devastatin­g impact of side effects caused by the injectable agents”.

Known side effects of the injectable include kidney failure and hearing loss‚ while the drug has only proven effective in 50% of cases.

“Experience with bedaquilin­e demonstrat­es improved clinical outcomes in people living with MDR-TB‚ and initial evidence shows that it can be safely and effectivel­y used in place of the toxic injectable‚” Dr Anja Reuter‚ of Doctors Without Borders‚ said.

Reuter is stationed in Khayelitsh­a, where the organisati­on has run a TB treatment programme for 11 years.

“There is no question we should be offering people the best options we have for more effective and less toxic treatment‚ but progress on this agenda has to date been slow in most countries,” she said. –

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