The Independent on Saturday

New cure for blocked, runny noses going to be a gas

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FIRING laughing gas up the nose could be a radical new treatment for blocked and runny noses.

Ice-cold nitrous oxide gas is delivered through a balloon on the end of a blow torchlike device.

The treatment destroys tissue that produces symptoms such as sneezing, nasal itching and congestion.

Rhinitis, which affects more than one in five people in the UK, is inflammati­on of the inside of the nose.

It can be caused by an allergy or by swollen blood vessels. This swelling blocks the nasal passages and also stimulates the glands in the nose to produce mucus, resulting in a blocked or runny nose.

Treatments for chronic rhinitis usually include nasal sprays that contain steroids. In more severe cases patients may need surgery.

The new treatment, which freezes the nasal passages, could be a fast-acting and potentiall­y safer alternativ­e. It uses cryotherap­y, a technique where freezing is harnessed to destroy unwanted tissue.

Inhaled forms of nitrous oxide are used in surgery as a form of anaesthesi­a. With the new treatment the gas is “chilled”.

The device, known as ClariFix, has a handle with a small canister of liquid-nitrous oxide attached at one end, and a long probe with a balloon inside at the other.

The probe is inserted into the nose and the doctor then presses a trigger on the handle. This causes a change in pressure and makes the nitrous oxide partially evaporate and rapidly cool as it moves and enters the balloon. The result is an ice-cold ball in the balloon at the end of the ClariFix device. This ball is held against the tissue, causing it to shrink and die.

Results from a 27-patient study by the maker, US-based company Arrinex, demonstrat­ed that the treatment was safe and led to a 60% improvemen­t in symptoms. More trials are under way in the US and New Zealand, where patients will receive one or two treatments in each nostril and have their symptoms monitored for three months.

A chilli spray could also help tackle rhinitis, researcher­s at the University Hospitals Leuven in Belgium have found. They gave rhinitis patients a nasal spray which contains capsaicin, the active ingredient in chilli peppers, to use daily for three months.

Results published in the journal Allergy showed 6879% of patients benefited and 32% had a major reduction in symptoms.

It is thought that capsaicin triggers a unique reaction in the nerves where after an initial inflammato­ry response, they stop reacting to any stimuli. This in turn relieves rhinitis symptoms. – Daily Mail

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