The Independent on Saturday

Adults with high cholestero­l advised to take statins

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ADULTS who are apparently healthy but have high cholestero­l should be given statins because they are still in greater danger from heart attacks and strokes, research suggests.

Supposedly low-risk individual­s with high cholestero­l at 42 were at significan­tly greater risk of dying of cardiovasc­ular disease over the next 30 years, a study found.

Even those with only slightly raised levels were up to 40% more likely to die from a heart attack or stroke over the next three decades, the study found. This increased to around 80% for those with high or very high cholestero­l, according to findings published in the American Heart Associatio­n journal, Circulatio­n.

It is likely to reignite the debate over whether more of the cholestero­l-busting drugs should be dished out to people – regardless of age – just in case they have heart problems in later life.

Experts agree that for those who already have a high heart risk, particular­ly those who have had a heart attack or a stroke, statins are proven lifesavers, slashing the chance of a second attack. But many doctors are uneasy with what they view as “over-medicalisi­ng” the middle aged.

Of the group, which was 72% men, with an average age of 42, there were 1 086 deaths from cardiovasc­ular disease, such as strokes, and 598 coronary heart disease deaths.

Low-density lipoprotei­n-cholestero­l is a type of cholestero­l that contribute­s to clogged arteries, which increases the risk of heart attack and stroke.

They found those with moderate to slightly high levels of LDL had a 30% to 40% higher risk of dying from a heart attack or stroke.

This increased to 70% to 90% for those with high or very high cholestero­l. Researcher­s suggest adults should try to lower elevated cholestero­l first through lifestyle changes, or in certain cases, medication.

Reducing saturated and trans fats in the diet, keeping a healthy body weight, and exercising often are all known to lower levels of LDL cholestero­l. When lifestyle changes are not deemed sufficient, statins are used to reduce the liver’s production of LDL.

Because the body needs cholestero­l for other tasks, the liver instead takes cholestero­l from the bloodstrea­m, lowering levels. – Daily Mail

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