Daily Mirror (Sri Lanka)

Indian pilots grounded after ‘mid-air row

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An Indian airline said yesterday it had grounded two pilots over allegation­s they had a fight and both briefly stormed out of the cockpit during a New Year’s Day flight from London to Mumbai.

Jet Airways is investigat­ing claims that a male pilot slapped his female colleague during a heated argument while the plane was in the air with 324 passengers on board.

Reports in several Indian newspapers, quoting unnamed sources, said the mid-air altercatio­n led the female pilot to leave the cockpit in tears and she had to be persuaded to go back in by cabin crew.

At one point the male pilot also left the cockpit, leaving the controls briefly unattended, the Times of India claimed. “A misunderst­anding occurred between the cockpit crew... However, the same was quickly resolved amicably and the flight... continued its journey to Mumbai, landing safely,” Jet said in a statement.

“The airline has reported the incident to the Directorat­e General of Civil Aviation (DGCA) and the concerned crew have been derostered pending an internal investigat­ion that has since been initiated,” it added.

The flight departed London around 1000 GMT on Monday and arrived in India’s financial capital on schedule around nine hours later at midnight local time.

“At Jet Airways, safety of guests, crew and assets is of paramount importance and the airline has zero tolerance for any action of its employees that compromise­s safety,” the airline said in its statement.

Europe’s largest privately held biotech company, Germany-based Biontech, has raised US $ 270 million to support its work in developing personalis­ed immunother­apies for cancer, ahead of an expected eventual stock market flotation.

Overall, the company has brought in close to US $ 950 million since it was founded in 2008 -- taking account of initial seed funding, grants and partnershi­p deals with big drugmakers -- giving it war chest to finance operations well into 2019.

Chief Operating Officer Sean Marett told Reuters the group would go public at some stage, given the capital-intensive nature of its business, although an initial public offering (IPO) was unlikely this year.

“Inevitably, in the end we will IPO just because of the size and the capital demands required by individual­ised approaches to treatment. You have to invest enormously in manufactur­ing,” he said.

Biontech hit the headlines in July when its experiment­al personalis­ed cancer vaccine, tailored to the tumours of individual patients, kept disease in check in an early-stage clinical trial.

The approach offers a way to widen the use of a new generation of immunother­apy drugs from the likes of Merck & Co, Bristol-myers Squibb and Roche that currently only work for a limited number of patients.

By adding a personalis­ed cancer vaccine, scientists believe it should be possible to improve substantia­lly the effectiven­ess of such immune-boosting medicines.

Biontech has already signed a US $ 310 million deal with Roche allowing the Swiss drugmaker to test the vaccine with its marketed immunother­apy drug Tecentriq.

The individual­ised vaccine uses so-called messenger RNA to carry code for making mutated proteins that are specific to a patient’s tumour, prompting specialist T-cells to step up their attack on cancer cells.

Biontech, which has around 700 employees at sites in Germany -- more than any other unlisted biotech firm in Europe -is also working on other cancerfigh­ting technologi­es, including antibodies, cell therapies and small molecules.

In addition to the deal with Roche’s Genentech unit, it has corporate partnershi­ps with Eli Lilly, Sanofi, Genmab and Bayer Animal Health.

Mainz-based Biontech has yet to make a profit and has been bankrolled for the past decade by majority owners Thomas and Andreas Struengman­n, who sold their generic drugs business Hexal to Novartis in 2005.

The latest Series A financing, announced yesterday, includes a fresh commitment by the Struengman­ns, alongside investment­s from Redmile Group, Janus Henderson Investors, Invus, Fidelity and other European family offices.

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