Daily Mirror (Sri Lanka)

“ELIMINATIN­G” ..... ”CRUSHING” COVID IS POSSIBLE AND THESE COUNTRIES ARE THE SUPERSTARS

- By Dr Ravi P. Rannan-eliya

Ever since the key numbers for the Covid-19 virus became clear in mid-february, it was obvious that all countries would end up trying to control its spread. The alternativ­e of letting the virus rampage unchecked through a country would always end up being too awful for any government, however stubborn or stupid, to accept. Unfortunat­ely, there has been a lot of confusion about the various strategies that countries could adopt, with a whole new lexicon of terms being thrown around in the media and by experts, and often used inconsiste­ntly. Welcome to our new world of “flattening the curve”, “hammer and dance”, mitigation, eliminatio­n, suppressio­n … and the list goes on. But ultimately, all these strategies boil down to just two – ”Mitigation” and “Eliminatio­n”, and which of these countries choose is often a matter of how much short term pain they are willing to suffer for longterm benefits.

MITIGATION

Mitigation aims to reduce the virus to a level that does not overwhelm a critical part of the system. A common concern is with how many ICU beds a country has, but it could also be how much contact tracing or testing capacity a country has. Mitigation tolerates continuous spread of the virus, but the goal is to avoid case numbers ever peaking above the level that the system cannot cope with. For this reason, it’s also called “flattening the curve”. Most countries have adopted this approach, including the USA, UK and Europe.

To implement mitigation, a country first has to slow down the spread of the virus and get new cases numbers coming down. Then, when it assesses numbers are manageable, it can gradually relax restrictio­ns it has imposed to open up the economy, whilst still living with significan­t numbers of new COVID cases each day. In practice, this would not be the end of it. These countries would still need periodical­ly to tighten restrictio­ns whenever case numbers start to rise, to get them down again to a manageable level. It’s been estimated that this on-off-on approach might still leave most Western economies under lockdown for significan­t periods of time. but it might allow them to open up their economies faster.

ELIMINATIO­N

Eliminatio­n aims to stop significan­t, the sustained transmissi­on of the virus inside the country altogether. It is sometimes also called “suppressio­n” and happens to be the core of what has been called “hammer and dance”—an approach the GMOA has pushed but did not invent.

Eliminatio­n does not mean zero cases. First, countries will continue to have cases in foreign arrivals. As long as these people don’t infect anyone locally, this is not a concern. Second, they will likely have a very low level of continuing local spread because of hidden cases. The best example of this is China. Despite going many days with zero local cases, China continues to report sporadic local cases, typically just one or two every few days. This happens because many COVID infections are never detected, so zero reported cases for two or even four weeks does not guarantee zero

viruses inside a country. In an eliminatio­n strategy, the goal is to keep these local cases as close to zero as possible, say one or two a week or month, and to have sufficient controls in place to prevent these numbers

increasing. China, Taiwan and New Zealand are aiming at this outcome.

To implement eliminatio­n, a country needs to make a huge initial effort to get cases of local infection down to zero or near zero, and then it needs to have continuing measures in place to slow down the hidden spread of virus between people sufficient­ly that numbers of new cases

remain flat and sporadic. To use technical jargon, this means reducing the effective reproducti­on number (Reff) substantia­lly below 1.0 to get to (near) zero cases, and then maintainin­g Reff at or below 1.0 to keep numbers from rising again.

WHY AREN’T COUNTRIES GOING FOR ELIMINATIO­N?

Although China had proved by early April that COVID eliminatio­n is possible, most countries are not aiming for eliminatio­n. One reason is that they believe that the short-term pain of getting cases down to near zero is not worth it. They believe that it’s better to live with a simmering epidemic and keep businesses open than shut everything down. In China, getting to zero involved locking down Hubei province with 60 million people for three months and significan­t controls in the rest of the country. Even then, three months was probably not long enough for Hubei, as China has reported a new cluster of cases there in the past few days. Another reason is that countries think that it is not realistic to do what China did.

I think that the belief that the costs for businesses and the economy are less with mitigation than with eliminatio­n is plain

wrong, but I won’t get into that here beyond noting that the only major economy that may escape recession this year is China. Instead, I want to focus on whether it is feasible for other countries to replicate China’s eliminatio­n success. One way to start answering this is to ask: “Are there any countries, other than China, that have been able to reduce case numbers fast enough to put them on a path to near-zero cases as required for eliminatio­n?” This is particular­ly relevant since many, including here in Sri Lanka, still dismiss eliminatio­n as unrealisti­c. And of course, there may be things that we can learn from any successes to do better ourselves.

ARE ANY COUNTRIES OTHER THAN CHINA ACHIEVING ELIMINATIO­N?

The media, pundits and others frequently highlight various countries as being COVID stars, including Sri Lanka. Unfortunat­ely, these claims often reflect prejudices about what works, a desire to push particular countries, or are not based on hard evidence. For example, some people tout Sweden as a country that is managing COVID well, but they ignore its death rate, one of the highest in the world.

To answer this question without letting our own biases get in the way, we need to let the data speak. So, what I and my colleagues at IHP (Nilmini Wijemunige, Nishani Gunawardan­a) did was to take the global data and look for any countries which have been able by end-april:

(1) To reduce the trend in new cases by at least 95% from whatever their peak infection rate was in March, AND

(2) Had fewer than 10 cases in the last week of April or less than one case per 100,000 people.

We focus on percentage reduction (1) and not the reduction in case numbers because this is a much better indication of how well a country’s efforts are controllin­g virus transmissi­on (see

Box). We also ignored countries with fewer than 100 cases in total by end-april, as it is difficult to assess the trend when numbers are small.

When we analyzed the data for all 141 territorie­s (I am going to call them countries for ease of reference), which had reported more than 100 cases by end-april, we found only 14 that met our criteria. These COVID super-performers consist of six high-income countries in the Asia-pacific region: Australia, Brunei, Hong Kong, Korea, New Zealand and Taiwan; three other high-income countries: the Faroe Islands, Iceland and Trinidad and Tobago; and five developing countries: Cambodia, China, Mauritius, Montenegro and Vietnam

. As illustrate­d in the first chart, these countries were able to reduce the number of new cases by more than 95% between their highest numbers in March and the end of April, and at their rate of reduction, all of them would be on track to achieve zero or close to zero cases within another month, if they hadn’t already done so.

Incidental­ly as shown in the chart, Sri Lanka did not make it into this group of Eliminatio­n Superstars, but not because of the navy cluster. If we exclude the navy cases, we still had a much higher number of cases involving arrivals infecting locals than seems to have been the case in the other countries in the list, and so our case trend was not sufficient­ly reduced by end-april to qualify.

I should emphasize that I don’t have any idea what Montenegro has done, and I have some suspicions about the data from Cambodia. But based purely on looking at the data, these fourteen are the countries that we should be looking most closely at. In the second chart, you can see how different the course of the COVID epidemic has been in this group of countries compared with the rest of the world. This underlines that whilst Sri Lanka has done better than most of the world, it has not done as well as the COVID superstars. Whilst COVID numbers continue to rise in the rest of the world, these COVID superstars largely crushed the epidemic before May Day. With the exception of Korea, all of them did this in less than six weeks. They prove that eliminatio­n is possible within a very short time outside China.

What these countries also demonstrat­e is that eliminatin­g COVID is possible in a wide range of settings. Although many are high-income countries, Cambodia and Vietnam are poorer than Sri Lanka, and they range in size from some of the smallest countries in the world to China, the largest. They are also located in all parts of the world from the tropics to near the Arctic and range from communist one-party states to Western democracie­s. This suggests that what makes them different is probably something to do with how they managed COVID. But it is not immediatel­y clear what this is since they don’t appear to have adopted identical policies. For example, several of them—hong Kong, Taiwan, Iceland and Vietnam—have not imposed national lockdowns. However, most do appear to have done far more COVID testing than Sri Lanka has, but without digging deeper it is not possible to conclude what really made a difference and what we might learn from them to do better. I leave this for my next article.

Dr Ravi P. Rannan-eliya is Executive Director of the Institute for Health Policy (IHP). He trained as a physician at Cambridge, and in public health and economics at Harvard. The views and opinions expressed in this article are his personal views, more of which can be found at his blog site – “Personal comment” at http://www.ihp.lk/blogs/ravi.

As illustrate­d in the first chart, these countries were able to reduce the number of new cases by more than 95% between their highest numbers in March and the end of April, and at their rate of reduction, all of them would be on track to achieve zero or close to zero cases within another month, if they hadn’t already done so.

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 ?? Source: Analysis by Ravi Rannan-eliya, Nilmini Wijemunige and Nishani Gunawardan­a (IHP) of data from Johns Hopkins University (https://github.com/cssegisand­data/covid-19) and Sri Lankan media reports. ??
Source: Analysis by Ravi Rannan-eliya, Nilmini Wijemunige and Nishani Gunawardan­a (IHP) of data from Johns Hopkins University (https://github.com/cssegisand­data/covid-19) and Sri Lankan media reports.
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